School of Life Science

Beijing Institute of Technology

460 Article
77 Review article
56 Conference contribution
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2025
A 2D Shaping 3D Strategy to Construct Hierarchical Microstructures Based on Heterogeneous Wettability
Li, H., Li, K., Yu, X., Zhao, W., Li, A., Cai, Z., Yuan, R., Liu, Q., Liu, W., Li, M. & Song, Y., 2025, (Accepted/In press) In: Advanced Functional Materials.
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A Chiral Porous Organic Polymer Used as the Stationary Phase for High-Resolution Gas Chromatography Separations
Wang, W., Wang, Z., Wang, Y., Sun, L., Zhang, J., Zhang, Y. & Luo, A., Jan 2025, In: Chirality. 37, 1, e70011.
Research output: Contribution to journal › Article › peer-review
Advances in bio-based wearable flexible sensors
Zhang, Z., Feng, B., Yan, J., Zhao, W. & Sun, J., 7 Jan 2025, In: Green Chemistry. 27, 6, p. 1604-1619 16 p.
Research output: Contribution to journal › Review article › peer-review
A particle counting immunosensor for the sensitive detection of ochratoxin A via click chemistry-mediated signal amplification
Chen, R., Dong, Y., Li, S., Ma, X., Pang, C., Wang, S., Zhang, J. & Chen, Y., 5 May 2025, In: Journal of Hazardous Materials. 488, 137381.
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Application of psychobiotics in clinical treatment of mental disorders: Neurodevelopmental disorders, neurodegenerative diseases, depression and anxiety
Cui, J., Wang, W., Tang, Y., Feng, S., Liu, H. & Hao, Z., 2025, (Accepted/In press) In: Interdisciplinary Medicine.
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Artificial Intelligence-Based Approaches for AAV Vector Engineering
Tan, F., Dong, Y., Qi, J., Yu, W. & Chai, R., 2025, (Accepted/In press) In: Advanced Science.
Research output: Contribution to journal › Review article › peer-review

Open Access
Correction to “AAV-Mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration”
Zhang, L., Chen, X., Wang, X., Zhou, Y., Fang, Y., Gu, X., Zhang, Z., Sun, Q., Li, N., Xu, L., Tan, F., Chai, R. & Qi, J., 3 Feb 2025, In: Advanced Science. 12, 5, 2416025.
Research output: Contribution to journal › Comment/debate

Open Access
Current AAV-mediated gene therapy in sensorineural hearing loss
Qi, J., Fu, X., Zhang, L., Tan, F., Li, N., Sun, Q., Hu, X., He, Z., Xia, M. & Chai, R., Jan 2025, In: Fundamental Research. 5, 1, p. 192-202 11 p.
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3 Citations (Scopus)
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Customization of Ethylene Glycol (EG)-Induced BmoR-Based Biosensor for the Directed Evolution of PET Degrading Enzymes
Li, M., Chen, Z., Zhang, W., Wu, T., Qi, Q. & Huo, Y. X., 2025, (Accepted/In press) In: Advanced Science.
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Digital microfluidics with integrated Raman sensor for high-sensitivity in-situ bioanalysis
Dong, W., Fu, R., Zhang, N., Zhao, J., Ma, Y., Cui, H., Zhang, J., Zhao, Z., Li, H., Zhao, Y., Lu, Y., Chen, Z., Xu, T., Xie, H., Yu, Q. & Zhang, S., Mar 2025, In: Biosensors and Bioelectronics. 271, 117036.
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2 Citations (Scopus)
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Engineering conductive covalent-organic frameworks enable highly sensitive and anti-interference molecularly imprinted electrochemical biosensor
Haotian, R., Zhu, Z., Zhang, H., Lv, T., Tang, S., Zhang, J., Luo, A. & Liang, A., 1 Apr 2025, In: Biosensors and Bioelectronics. 273, 117195.
Research output: Contribution to journal › Article › peer-review
Enhancing water toxicity determination sensitivity by using TMAO as electron acceptor of inward extracellular electron transfer in electrochemically active bacteria
Zang, Y., Cao, B., Yi, X., Zha, F., Ge, Y., Liu, H. & Yi, Y., Aug 2025, In: Bioelectrochemistry. 164, 108925.
Research output: Contribution to journal › Review article › peer-review
Erratum: Critical role of TPRN rings in the stereocilia for hearing (Molecular Therapy (2024) 32(1) (204–217), (S1525001623006123), (10.1016/j.ymthe.2023.11.011))
Qi, J., Tan, F., Zhang, L., Zhou, Y., Zhang, Z., Sun, Q., Li, N., Fang, Y., Chen, X., Wu, Y., Zhong, G. & Chai, R., 8 Jan 2025, In: Molecular Therapy. 33, 1, p. 419-420 2 p.
Research output: Contribution to journal › Comment/debate
Extracellular vesicle-packed microRNAs profiling in Alzheimer's disease: The molecular intermediary between pathology and diagnosis
Arif, S., Qazi, T. J., Quan, Z., Ni, J., Li, Z., Qiu, Y. & Qing, H., Feb 2025, In: Ageing Research Reviews. 104, 102614.
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Fully Inter-restricted Assembly of Aggregation-Induced Emission Luminogens and Polymers Enables Ultra-bright Nanoparticles for Sensitive Point-of-Care Diagnosis
Chen, X., Liu, Q., Zhang, J., Tan, L., Li, J., Ke, M. L., Tang, B. Z. & Li, Y., 18 Feb 2025, In: ACS Nano. 19, 6, p. 6221-6235 15 p.
Research output: Contribution to journal › Article › peer-review
Long Lifetime and High Reusability of Water Toxicity Determination Based on Electrochemically Active Bacteria
Yi, Y., Feng, Y., Yi, X., Zha, F., Hao, Z., Yu, D., Liu, H., Ge, Y. & Luo, A., 14 Feb 2025, In: ACS ES and T Engineering. 5, 2, p. 414-423 10 p.
Research output: Contribution to journal › Article › peer-review
Low-potential bionic electrochemiluminescence sensing platform based on SnS₂/CuNWs synergistic promotion for highly selective detection of glycocholic acid
Wang, Y., Tang, S., Liu, M., Wang, W., Liang, A. & Luo, A., 22 Jan 2025, In: Analytica Chimica Acta. 1336, 343537.
Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
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Novel Feruloyl Esterase from Rehmannia glutinosa Endophyte Alternaria botrytis RYF1 and Its Application in the Production of Verbasoside and Hydroxysalidroside
Ban, Y., Yang, H., Jiang, J., Xia, T., Pang, Y., Cheng, X., Yang, Y., Lv, B. & Feng, Y., 2025, (Accepted/In press) In: Journal of Agricultural and Food Chemistry.
Research output: Contribution to journal › Article › peer-review
One-round-per-day CRISPR genome editing of E. coli for engineering green-chemical overproducer
Liang, Z., Ye, Z., Xia, Y., Du, X., Sun, L., Ma, X., Guo, S. & Huo, Y. X., 1 Jan 2025, In: Chemical Engineering Journal. 503, 158453.
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Preparation of novel chiral stationary phases based on chiral metal-organic cages enable extensive HPLC enantioseparation
Wang, Z., Wang, W., Sun, L., Liang, A., Duan, J., Zhang, Y., Tang, B. & Luo, A., 1 Feb 2025, In: Analytica Chimica Acta. 1337, 343541.
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Rapid adaptation of Bacillus thuringiensis to alkaline environments via the L-lactate metabolism pathway regulated by the CRP/FNR family regulator LtmR
Peng, Q., Qin, J., Xu, H., Kao, G., Yang, F., Sun, Z., Zhang, X., Slamti, L., Guo, S. & Song, F., Mar 2025, In: Pesticide Biochemistry and Physiology. 208, 106255.
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Recent advances in biosynthesis of non-canonical amino acids and their potentials in strain engineering
Hou, Z., Tuo, J., Ma, X. & Huo, Y. X., Mar 2025, In: Results in Engineering. 25, 103641.
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Spatial transcriptomic characterization of a Carnegie stage 7 human embryo
Cui, L., Lin, S., Yang, X., Xie, X., Wang, X., He, N., Yang, J., Zhang, X., Lu, X., Yan, X., Guo, Y., Zhang, B., Li, R., Miao, H., Ji, M., Zhang, R., Yu, L., Xiao, Z., Wei, Y. & Guo, J., 2025, (Accepted/In press) In: Nature Cell Biology. e13298.
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Study on Recovery Strategy of Hearing Loss & SGN Regeneration Under Physical Regulation
Li, Z., Gao, Y., Chen, X., Xu, L., Li, Z. & Chai, R., 3 Feb 2025, In: Advanced Science. 12, 5, 2410919.
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The interconnective role of the UPS and autophagy in the quality control of cancer mitochondria
Xu, W., Dong, L., Dai, J., Zhong, L., Ouyang, X., Li, J., Feng, G., Wang, H., Liu, X., Zhou, L. & Xia, Q., Dec 2025, In: Cellular and Molecular Life Sciences. 82, 1, 42.
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生物质基抗菌材料制备及其应用进展
Translated title of the contribution: Progress in preparation and application of biomass-based antibacterial materialsXiao, W., Zhu, M., Zhang, K., Liu, Y., Zhao, W., Yan, J. & Sun, J., 1 Jan 2025, In: Scientia Sinica Chimica. 55, 1, p. 168-187 20 p.
Research output: Contribution to journal › Review article › peer-review
2024
3D reconstruction of a gastrulating human embryo
Xiao, Z., Cui, L., Yuan, Y., He, N., Xie, X., Lin, S., Yang, X., Zhang, X., Shi, P., Wei, Z., Li, Y., Wang, H., Wang, X., Wei, Y., Guo, J. & Yu, L., 23 May 2024, In: Cell. 187, 11, p. 2855-2874.e19
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9 Citations (Scopus)
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Citation Indexes: 9
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AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial
Lv, J., Wang, H., Cheng, X., Chen, Y., Wang, D., Zhang, L., Cao, Q., Tang, H., Hu, S., Gao, K., Xun, M., Wang, J., Wang, Z., Zhu, B., Cui, C., Gao, Z., Guo, L., Yu, S., Jiang, L. & Yin, Y. & 7 others, Zhang, J., Chen, B., Wang, W., Chai, R., Chen, Z. Y., Li, H. & Shu, Y., 25 May 2024, In: The Lancet. 403, 10441, p. 2317-2325 9 p.
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82 Citations (Scopus)
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Citation Indexes: 76
Patent Family Citations: 1
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AAV-based gene replacement: The promise of gene therapy for deafness
Qi, J., Zhang, L. & Chai, R., 11 Jun 2024, In: Molecular Therapy Nucleic Acids. 35, 2, 102181.
Research output: Contribution to journal › Comment/debate

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2 Citations (Scopus)
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AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration
Zhang, L., Chen, X., Wang, X., Zhou, Y., Fang, Y., Gu, X., Zhang, Z., Sun, Q., Li, N., Xu, L., Tan, F., Chai, R. & Qi, J., 7 Aug 2024, In: Advanced Science. 11, 29, 2304551.
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Open Access
11 Citations (Scopus)
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Citation Indexes: 10
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AAV-mediated Gene Therapy for Hereditary Deafness: Progress and Perspectives
Zhang, L., Tan, F., Qi, J., Lu, Y., Wang, X., Yang, X., Chen, X., Zhang, X., Fan, J., Zhou, Y., Peng, L., Li, N., Xu, L., Yang, S. & Chai, R., 18 Dec 2024, In: Advanced Science. 11, 47, 2402166.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Citations (Scopus)
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AAV-Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness
Qi, J., Tan, F., Zhang, L., Lu, L., Zhang, S., Zhai, Y., Lu, Y., Qian, X., Dong, W. X., Zhou, Y., Zhang, Z., Yang, X., Jiang, L., Yu, C., Liu, J., Chen, T., Wu, L., Tan, C., Sun, S. & Song, H. & 5 others, Shu, Y., Xu, L., Gao, X., Li, H. & Chai, R., 20 Mar 2024, In: Advanced Science. 11, 11, 2306788.
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45 Citations (Scopus)
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Citation Indexes: 42
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AAV-regulated Serpine2 overexpression promotes hair cell regeneration
Sun, Q., Tan, F., Wang, X., Gu, X., Chen, X., Lu, Y., Li, N., Qian, X., Zhou, Y., Zhang, Z., Wang, M., Zhang, L., Tong, B., Qi, J. & Chai, R., 10 Dec 2024, In: Molecular Therapy Nucleic Acids. 35, 4, 102396.
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2 Citations (Scopus)
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A chiral emissive porous organic cage used for high-resolution gas chromatography separations
Wang, Z., Wang, W., Tang, B., Sun, L., Zhang, F. & Luo, A., 30 Jan 2024, In: New Journal of Chemistry. 48, 10, p. 4273-4280 8 p.
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A codon-based live-cell biomonitoring system for assessing intracellular phenylalanine bioavailability in cyanobacteria
Jin, H., Zhang, J., Wang, Y., Ge, W., Jing, Y., Cao, X., Huo, Y. & Fu, Y., 15 Jan 2024, In: Biosensors and Bioelectronics. 244, 115792.
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2 Citations (Scopus)
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Advances in novel biosensors in biomedical applications
Liang, A., Zhao, W., Lv, T., Zhu, Z., Haotian, R., Zhang, J., Xie, B., Yi, Y., Hao, Z., Sun, L. & Luo, A., 1 Dec 2024, In: Talanta. 280, 126709.
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1 Citation (Scopus)
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A microfluidic-based gut-on-a-chip model containing the gut microbiota of patients with depression reveals physiological characteristics similar to depression
Wang, W., Liu, Y., Yao, Z., Chen, D., Tang, Y., Cui, J., Zhang, J., Liu, H. & Hao, Z., 4 Apr 2024, In: Lab on a Chip. 24, 9, p. 2537-2550 14 p.
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A mixture of extracts from natural ingredients reduces the neurotoxic polarization of microglia via modulating NF-κB/NF-E2-related factor 2 activation
Gui, S., Ni, J., Mizutani, S., Shigematsu, N., Nakanishi, H., Kashiwazaki, H. & Wu, Z., May 2024, In: Food Science and Nutrition. 12, 5, p. 3745-3758 14 p.
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AND-Gate Logic Förster Resonance Energy Transfer/Magnetic Resonance Tuning Nanoprobe for Programmable Antitumor Immunity Imaging
Ma, X., Mao, M., Liu, Z., Liang, C., He, J., Qu, Y., Xu, L., Cheng, R., Zhuang, W., Lei, Y., Nie, W., Yuan, L., Pang, D. W. & Xie, H. Y., 20 Nov 2024, In: Journal of the American Chemical Society. 146, 46, p. 31873-31884 12 p.
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A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
Zhang, J., Chen, Z., Lei, Y. & Wen, J., Mar 2024, In: Diagnostics. 14, 5, 482.
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A novel molecular imprinted electrochemical biosensor for sensitive determination of Ganoderic acid A
Li, W., Xie, Y. & Liang, A., 2024, In: Journal of Physics: Conference Series. 2713, 1, 012076.
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Open Access
An unlabeled electrochemical sensor for the simultaneous detection of homocysteine and uric acid based on molecularly imprinted recognition for prediction of cardiovascular disease risk
Liu, M., Tang, S., Wang, Y., Liang, A. & Luo, A., May 2024, In: Microchemical Journal. 200, 110376.
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5 Citations (Scopus)
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Application Evaluation and Performance-Directed Improvement of the Native and Engineered Biosensors
Li, M., Chen, Z. & Huo, Y. X., 25 Oct 2024, In: ACS Sensors. 9, 10, p. 5002-5024 23 p.
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1 Citation (Scopus)
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Application of Oriented Molecular Imprinting Biosensors in Biomarker Detection
Lv, T., Chen, T., Zhu, Z., Haotian, R., Luo, A. & Liang, A., Dec 2024, In: Journal of Analysis and Testing. 8, 4, p. 553-568 16 p.
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3 Citations (Scopus)
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A ratiometric molecular imprinted electrochemiluminescence sensor based on enhanced luminescence of CdSe@ZnS quantum dots by MXene@NaAsc for detecting uric acid
Liu, M., Wang, Y., Tang, S., Wang, W., Liang, A. & Luo, A., Apr 2024, In: Bioelectrochemistry. 156, 108610.
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6 Citations (Scopus)
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ARBUR, a machine learning-based analysis system for relating behaviors and ultrasonic vocalizations of rats
Chen, Z., Jia, G., Zhou, Q., Zhang, Y., Quan, Z., Chen, X., Fukuda, T., Huang, Q. & Shi, Q., 21 Jun 2024, In: iScience. 27, 6, 109998.
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A α-L-rhamnosidase from Echinacea purpurea endophyte Simplicillium sinense EFF1 and its application in production of Calceorioside B
Ban, Y., Yang, H., Jiang, J., Wang, C., Lv, B. & Feng, Y., Jun 2024, In: International Journal of Biological Macromolecules. 270, 132090.
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3 Citations (Scopus)
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Bacterial film-based degradable triboelectric nanogenerator for both contact and non-contact sensing
Zhang, B., Zou, Y., Liu, M., Wang, E., Cui, X., Wang, Y., Xue, J., Li, Y., Deng, Y. & Li, Z., 15 Nov 2024, In: Chemical Engineering Journal. 500, 156711.
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2 Citations (Scopus)
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Bioactive hydrogels loaded with BMSC-EXOs and GDNF for synergistically spinal cord injury repairing
Cheng, H., Zhang, H., Hu, Y., Wang, Y., Tian, L., Qi, Y., Ren, L., Zhang, B., Zheng, S., Han, X., Ma, X., Bian, F., Wang, H., Liu, T. & Chai, R., Sept 2024, In: Composites Part B: Engineering. 284, 111618.
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5 Citations (Scopus)
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Biosynthesis of D-1,2,4-butanetriol promoted by a glucose-xylose dual metabolic channel system in engineered Escherichia coli
Zhang, L., Wang, J., Gu, S., Liu, X., Hou, M., Zhang, J., Yang, G., Zhao, D., Dong, R. & Gao, H., 25 Nov 2024, In: New Biotechnology. 83, p. 26-35 10 p.
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