. Advances in the synthesis of unnatural amino acids and unnatural proteins. Bioprocessing. 22,20(02):182-194. (Impact Factor 1.109, published in 2022-06)
[61] Zhenya Chen, Tongtong Chen, Shengzhu Yu, Yi-Xin Huo*. A high-throughput visual screening method for p-hydroxybenzoate hydroxylase to increase phenolic compounds biosynthesis. Biotechnol Biofuels Bioprod. 2022, 15(1): 1-15. (Impact factor 7.67, Publication Date 2022-05)
[60] Mengyuan Li, Yi-Xin Huo*, Shuyuan Guo*. CRISPR-Mediated Base Editing: From Precise Point Mutation to Genome-Wide Engineering in Nonmodel Microbes. Biology. 2022, 11(4): 571. (Impact Factor 5.007, published 2022-04)
[59] Jiheng Tian, Baowen Xing, Mengyuan Li, Changgeng Xu, Yi-Xin Huo*, Shuyuan Guo*. Efficient Large-Scale and Scarless Genome Engineering Enables the Construction and Screening of Bacillus subtilis Biofuel Overproducers. Int.J. Mol. Sci. 2022, 23, 4853. (Impact Factor 5.923, published 2022-04)
[58] Yuhui Du, Wei Song, Zhiqiu Yin, Shengbo Wu, Jiaheng Liu, Ning Wang, Hua Jin, Jianjun Qiao, Yi-Xin Huo*. Genomic Analysis Based on Chromosome-Level Genome Assembly Reveals an Expansion of Terpene Biosynthesis of Azadirachta indica. Front Plant Sci. 2022, 13: 853861. (Impact Factor 5.753, published from 2022-04)
[57] Bo Zheng, Yinchao He, Pengxiang Zhang, Yi-Xin Huo*, Yanbin Yin. Polyphenol Utilization Proteins in the Human Gut Microbiome. Appl Environ Microbiol. 2022 Feb 8; 88(3):e0185121. (Impact Factor 5.005, published on 2022-02)
[56] Tong Wu#, Zhenya Chen#, Shuyuan Guo, Cuiying Zhang, Yi-Xin Huo*. Engineering transcription factor BmoR mutants for constructing multifunctional alcohol biosensors. ACS Synth Biol. 2022, 11(3): 1251-1260 (Impact factor 5.249, Date of publication 2022-02)
[55] Shengzhu Yu, Bo Zheng, Zhenya Chen*, Yi-Xin Huo. Metabolic engineering of Corynebacterium glutamicum for producing branched chain amino acids. Microb Cell Fact.2021.20 (1): 1-14 (Impact factor 6.352, Date of publication 2021-12)
[54] Luyao Zhao, Zhenya Chen, Sheng Lin, Tong Wu, Shengzhu Yu, Yi-Xin Huo*. In Vitro Biosynthesis of Isobutyraldehyde Through the Establishment of a One-Step Self-Assembly-Based Immobilization Strategy.J Agr Food Chem.202.69 (48): 14609-19 (Impact factor 5.279, date of release 2021-11)
[53] Huiyan Wang#, Hao Guo#, Ning Wang*, Yi-Xin Huo*. Toward the Heterologous Biosynthesis of Plant Natural Products: Gene Discovery and Characterization. ACS Synth Biol.2021 (Impact Factor 5.249, published from 2021-11)
[52] Xiaoyan Ma#, Lianjie Ma#, Yi-Xin Huo*. Reconstructing the transcription regulatory network to optimize resource allocation for robust biosynthesis. Trends Biotechnol.2021 (Impact Factor 19.526, Publication date 2021-11)
[51] MA Xiaoyan, Wang Xueqin, Ma Lianjie,
. Advances in the synthesis of unnatural amino acids and unnatural proteins. Bioprocessing. 22,20(02):182-194. (Impact Factor 1.109, published in 2022-06)
[61] Zhenya Chen, Tongtong Chen, Shengzhu Yu, Yi-Xin Huo*. A high-throughput visual screening method for p-hydroxybenzoate hydroxylase to increase phenolic compounds biosynthesis. Biotechnol Biofuels Bioprod. 2022, 15(1): 1-15. (Impact factor 7.67, Publication Date 2022-05)
[60] Mengyuan Li, Yi-Xin Huo*, Shuyuan Guo*. CRISPR-Mediated Base Editing: From Precise Point Mutation to Genome-Wide Engineering in Nonmodel Microbes. Biology. 2022, 11(4): 571. (Impact Factor 5.007, published 2022-04)
[59] Jiheng Tian, Baowen Xing, Mengyuan Li, Changgeng Xu, Yi-Xin Huo*, Shuyuan Guo*. Efficient Large-Scale and Scarless Genome Engineering Enables the Construction and Screening of Bacillus subtilis Biofuel Overproducers. Int.J. Mol. Sci. 2022, 23, 4853. (Impact Factor 5.923, published 2022-04)
[58] Yuhui Du, Wei Song, Zhiqiu Yin, Shengbo Wu, Jiaheng Liu, Ning Wang, Hua Jin, Jianjun Qiao, Yi-Xin Huo*. Genomic Analysis Based on Chromosome-Level Genome Assembly Reveals an Expansion of Terpene Biosynthesis of Azadirachta indica. Front Plant Sci. 2022, 13: 853861. (Impact Factor 5.753, published from 2022-04)
[57] Bo Zheng, Yinchao He, Pengxiang Zhang, Yi-Xin Huo*, Yanbin Yin. Polyphenol Utilization Proteins in the Human Gut Microbiome. Appl Environ Microbiol. 2022 Feb 8; 88(3):e0185121. (Impact Factor 5.005, published on 2022-02)
[56] Tong Wu#, Zhenya Chen#, Shuyuan Guo, Cuiying Zhang, Yi-Xin Huo*. Engineering transcription factor BmoR mutants for constructing multifunctional alcohol biosensors. ACS Synth Biol. 2022, 11(3): 1251-1260 (Impact factor 5.249, Date of publication 2022-02)
[55] Shengzhu Yu, Bo Zheng, Zhenya Chen*, Yi-Xin Huo. Metabolic engineering of Corynebacterium glutamicum for producing branched chain amino acids. Microb Cell Fact.2021.20 (1): 1-14 (Impact factor 6.352, Date of publication 2021-12)
[54] Luyao Zhao, Zhenya Chen, Sheng Lin, Tong Wu, Shengzhu Yu, Yi-Xin Huo*. In Vitro Biosynthesis of Isobutyraldehyde Through the Establishment of a One-Step Self-Assembly-Based Immobilization Strategy.J Agr Food Chem.202.69 (48): 14609-19 (Impact factor 5.279, date of release 2021-11)
[53] Huiyan Wang#, Hao Guo#, Ning Wang*, Yi-Xin Huo*. Toward the Heterologous Biosynthesis of Plant Natural Products: Gene Discovery and Characterization. ACS Synth Biol.2021 (Impact Factor 5.249, published from 2021-11)
[52] Xiaoyan Ma#, Lianjie Ma#, Yi-Xin Huo*. Reconstructing the transcription regulatory network to optimize resource allocation for robust biosynthesis. Trends Biotechnol.2021 (Impact Factor 19.526, Publication date 2021-11)
[51] MA Xiaoyan, Wang Xueqin, Ma Lianjie,

Carbon neutral (see below for representative articles [52], [10], [8])
Carbon dioxide resource, carbon sequestration microorganisms to achieve high value carbon dioxide conversion
Gene editing (see below for representative articles [50], [46], [34])
Gene editing of prokaryotic and eukaryotic cells, and highly robust chassis host construction; Methodology development
Metabolic engineering (see below for representative articles [69], [66], [65], [58], [56], [43])
Construction of microbial synthetic Pathway and Efficient Production of Bulk Chemicals and drug intermediates
Enzyme engineering (see below for representative articles [67], [64], [35])
Plastic degrading enzyme; Research and development of Biosensors
Bioinformatics (see below for representative articles [58], [49])
Plant functional gene mining; Microbial evolution mechanism


Carbon neutral (see below for representative articles [52], [10], [8])
Carbon dioxide resource, carbon sequestration microorganisms to achieve high value carbon dioxide conversion
Gene editing (see below for representative articles [50], [46], [34])
Gene editing of prokaryotic and eukaryotic cells, and highly robust chassis host construction; Methodology development
Metabolic engineering (see below for representative articles [69], [66], [65], [58], [56], [43])
Construction of microbial synthetic Pathway and Efficient Production of Bulk Chemicals and drug intermediates
Enzyme engineering (see below for representative articles [67], [64], [35])
Plastic degrading enzyme; Research and development of Biosensors
Bioinformatics (see below for representative articles [58], [49])
Plant functional gene mining; Microbial evolution mechanism

2008-08 to 2011-07, Postdoctoral fellow, University of California, Los Angeles, Professor James C. Liao (Academician of the American Academy of Sciences, the American Academy of Engineering, the National Academy of Inventors, the Third World Academy of Sciences, Academia Sinica, Taiwan, currently President of Academia Sinica, Taiwan)
2006-05 to 2008-08, Postdoctoral Fellow, University of California, Los Angeles, Supervisor: Professor Jay D. Gralla
2002-09 to 2005-12, PhD, Molecular Microbiology and Virology, University of Paris 7 (joint training, PhD in both China and France), Supervisor: Researcher Annie Kolb
2000-09 to 2005-12, PhD, Biochemistry and Molecular Biology, Peking University, Supervisor: Professor Wang Yiping
1995-09 to 1999-06, Nankai University, Microbiology, B.S.

August 2023 - Present, Distinguished Professor (Second Class Professor), School of Life Sciences, Beijing Institute of Technology
2021-01 to August 2023, Beijing Institute of Technology, School of Life Sciences, Professor (Third Grade)
2019-10 till now, Deputy Dean (Graduate Student, Discipline), School of Life Sciences, Beijing Institute of Technology
2019-09 to now, Professor of Biotechnology, School of Life Sciences, Beijing Institute of Technology
2019-01-Now, Key Laboratory of Molecular Medicine and Biological Diagnosis and Treatment, Ministry of Industry and Information Technology, Beijing Institute of Technology, Deputy Director
2017-09 to 2020-12, Professor of Bioengineering, School of Life Sciences, Beijing Institute of Technology
2015-09 to 2020-12, School of Life Sciences, Beijing Institute of Technology, Professor
2014-11 to 2015-09, Laboratory Director, BioEnergy Research Center, Suzhou Institute for Advanced Technology, UCLA
2011-08 to 2015-09, Nantworks Group Easel Biotechnology Company, Project Director, Senior Researcher


August 2023 - Present, Distinguished Professor (Second Class Professor), School of Life Sciences, Beijing Institute of Technology
2021-01 to August 2023, Beijing Institute of Technology, School of Life Sciences, Professor (Third Grade)
2019-10 till now, Deputy Dean (Graduate Student, Discipline), School of Life Sciences, Beijing Institute of Technology
2019-09 to now, Professor of Biotechnology, School of Life Sciences, Beijing Institute of Technology
2019-01-Now, Key Laboratory of Molecular Medicine and Biological Diagnosis and Treatment, Ministry of Industry and Information Technology, Beijing Institute of Technology, Deputy Director
2017-09 to 2020-12, Professor of Bioengineering, School of Life Sciences, Beijing Institute of Technology
2015-09 to 2020-12, School of Life Sciences, Beijing Institute of Technology, Professor
2014-11 to 2015-09, Laboratory Director, BioEnergy Research Center, Suzhou Institute for Advanced Technology, UCLA
2011-08 to 2015-09, Nantworks Group Easel Biotechnology Company, Project Director, Senior Researcher