Lichao Sun

Assistant Professor (Associate Researcher), Master Supervisor
Contact us: sunlichao@bit.edu.cn
Admission Direction: Biology/Biotechnology and Engineering
Welcome students with a background in Microbiology/Synthetic biology/Chemical engineering/Artificial Intelligence/Bioinformatics!
Educational Experience:
2010-2016, Tsinghua University, PhD
2006-2010, Beijing University of Chemical Technology, BA
Work Experience:
2021-present, Pre-Appointed Assistant Professor, School of Life Sciences, Beijing Institute of Technology
2019-2020, University of Texas at Austin, Visiting Scholar, collaborator: Professor Hal Alper
2016-2021, Assistant Researcher, Institute of Agricultural Product Processing, Chinese Academy of Agricultural Sciences
Academic Part-time:
Member of the Youth Working Committee of the Chinese Society of BioEngineering
Expert of School-Enterprise Integration Professional Committee of China Technology Entrepreneurship Association
Frontiers in Synthetic Biology Review Editor Trends in Food Science and Technology, Critical Reviews in Biotechnology, Journal of Agricultural and Food Chemistry, Biotechnology and Bioengineering, Enzyme and Microbial Technology, AMB Express, Journal reviewer for Biotechnology and Bioprocess Engineering
Personal Honor:
The Third Prize of the 13th Beijing Basic Skills Competition for Young Teachers (2023)
First Prize of the 13th Basic Skills Competition for Young Teachers of Beijing Institute of Technology (2022)
Beijing Institute of Technology School of Life Science Curriculum Ideological and political Competition first prize (2022)
Research Direction:
Construction of microbial cell factories based on synthetic biotechnology, and biosynthesis of high-value compounds with carbon and nitrogen neutralization. By means of enzyme engineering, metabolic engineering and synthetic biology, combined with bioinformatics, machine learning and protein design technologies, the development of enabling technologies, the construction of artificial cell factories, the creation of high-performance catalytic components, and the dynamic regulation of metabolic pathways are carried out to achieve microbial refining of high value-added compounds and green biofabration. The research content includes but is not limited to:
1. Cell factory: Construction of artificial cell factory based on gene editing, high-throughput screening and omics technology, function optimization and prediction with the help of bioinformatics and machine learning
2. Functional components: Mining of new functional components and directed evolution, activity regulation of high-performance catalytic components, combined with protein design technology to achieve more efficient catalysis 3. Regulation strategy: Using dynamic regulation methods based on biosensing technology and machine learning methods to achieve balanced distribution of metabolic flow and optimize regulation strategy
4. Target products: Biosynthesis of high value-added compounds such as bulk chemicals and food additives
Research Project:
1. Natural Science Foundation Project of Hebei Province, Metabolic Regulation Strategy Based on Amino acid Resource Allocation and its Application in Isobutanol Production (C2023105022), 2023/01-2025/12, Director
2. Beijing Natural Science Foundation Project, Dynamic and Precise Regulation of Biobase isobutyraldehyde Synthesis Process (2222026), 2022/01-2024/12, Host
3. Research on Efficient Microbial Synthesis of Amino acid Derivatives, Science and Technology Innovation Program, Beijing Institute of Technology, 2021/03-2024/06, Host
4. Youth Project of National Natural Science Foundation of China, vanillin synthetase Feruloyl-CoA Ligase (FCS) substrate Recognition and Catalytic Mechanism (31700701), 2018/01-2020/12, Host
5. Open Project of State Key Laboratory of Bioreactor Engineering, Identification and catalytic mechanism of Carotenoid cracking oxygenase CSO2 substrate (2018OPEN13), 2018/09-2020/08, Host
Educational Reform Project:
1. Postgraduate Education and Teaching Reform Project of Beijing Institute of Technology, Research on Life science teaching reform facing the needs of Bioeconomy Development in the 14th Five-Year Plan, led by
2. Undergraduate Education and Teaching Reform Project of Beijing Institute of Technology, integrating ideological and political teaching innovation in the forefront of life science, chaired
3. Undergraduate Education and teaching reform project of Beijing Institute of Technology, implementing the basic teaching model reform of biological sciences based on interdisciplinary teaching, participating in
Representative Papers:
[15]
Assistant Professor (Associate Researcher), Master Supervisor
Contact us: sunlichao@bit.edu.cn
Admission Direction: Biology/Biotechnology and Engineering
Welcome students with a background in Microbiology/Synthetic biology/Chemical engineering/Artificial Intelligence/Bioinformatics!
Educational Experience:
2010-2016, Tsinghua University, PhD
2006-2010, Beijing University of Chemical Technology, BA
Work Experience:
2021-present, Pre-Appointed Assistant Professor, School of Life Sciences, Beijing Institute of Technology
2019-2020, University of Texas at Austin, Visiting Scholar, collaborator: Professor Hal Alper
2016-2021, Assistant Researcher, Institute of Agricultural Product Processing, Chinese Academy of Agricultural Sciences
Academic Part-time:
Member of the Youth Working Committee of the Chinese Society of BioEngineering
Expert of School-Enterprise Integration Professional Committee of China Technology Entrepreneurship Association
Frontiers in Synthetic Biology Review Editor Trends in Food Science and Technology, Critical Reviews in Biotechnology, Journal of Agricultural and Food Chemistry, Biotechnology and Bioengineering, Enzyme and Microbial Technology, AMB Express, Journal reviewer for Biotechnology and Bioprocess Engineering
Personal Honor:
The Third Prize of the 13th Beijing Basic Skills Competition for Young Teachers (2023)
First Prize of the 13th Basic Skills Competition for Young Teachers of Beijing Institute of Technology (2022)
Beijing Institute of Technology School of Life Science Curriculum Ideological and political Competition first prize (2022)
Research Direction:
Construction of microbial cell factories based on synthetic biotechnology, and biosynthesis of high-value compounds with carbon and nitrogen neutralization. By means of enzyme engineering, metabolic engineering and synthetic biology, combined with bioinformatics, machine learning and protein design technologies, the development of enabling technologies, the construction of artificial cell factories, the creation of high-performance catalytic components, and the dynamic regulation of metabolic pathways are carried out to achieve microbial refining of high value-added compounds and green biofabration. The research content includes but is not limited to:
1. Cell factory: Construction of artificial cell factory based on gene editing, high-throughput screening and omics technology, function optimization and prediction with the help of bioinformatics and machine learning
2. Functional components: Mining of new functional components and directed evolution, activity regulation of high-performance catalytic components, combined with protein design technology to achieve more efficient catalysis 3. Regulation strategy: Using dynamic regulation methods based on biosensing technology and machine learning methods to achieve balanced distribution of metabolic flow and optimize regulation strategy
4. Target products: Biosynthesis of high value-added compounds such as bulk chemicals and food additives
Research Project:
1. Natural Science Foundation Project of Hebei Province, Metabolic Regulation Strategy Based on Amino acid Resource Allocation and its Application in Isobutanol Production (C2023105022), 2023/01-2025/12, Director
2. Beijing Natural Science Foundation Project, Dynamic and Precise Regulation of Biobase isobutyraldehyde Synthesis Process (2222026), 2022/01-2024/12, Host
3. Research on Efficient Microbial Synthesis of Amino acid Derivatives, Science and Technology Innovation Program, Beijing Institute of Technology, 2021/03-2024/06, Host
4. Youth Project of National Natural Science Foundation of China, vanillin synthetase Feruloyl-CoA Ligase (FCS) substrate Recognition and Catalytic Mechanism (31700701), 2018/01-2020/12, Host
5. Open Project of State Key Laboratory of Bioreactor Engineering, Identification and catalytic mechanism of Carotenoid cracking oxygenase CSO2 substrate (2018OPEN13), 2018/09-2020/08, Host
Educational Reform Project:
1. Postgraduate Education and Teaching Reform Project of Beijing Institute of Technology, Research on Life science teaching reform facing the needs of Bioeconomy Development in the 14th Five-Year Plan, led by
2. Undergraduate Education and Teaching Reform Project of Beijing Institute of Technology, integrating ideological and political teaching innovation in the forefront of life science, chaired
3. Undergraduate Education and teaching reform project of Beijing Institute of Technology, implementing the basic teaching model reform of biological sciences based on interdisciplinary teaching, participating in
Representative Papers:
[15]

Construction of microbial cell factories based on synthetic biotechnology, and biosynthesis of high-value compounds with carbon and nitrogen neutralization. By means of enzyme engineering, metabolic engineering and synthetic biology, combined with bioinformatics, machine learning and protein design technologies, the development of enabling technologies, the construction of artificial cell factories, the creation of high-performance catalytic components, and the dynamic regulation of metabolic pathways are carried out to achieve microbial refining of high value-added compounds and green biofabration. The research content includes but is not limited to:
1. Cell factory: Construction of artificial cell factory based on gene editing, high-throughput screening and omics technology, function optimization and prediction with the help of bioinformatics and machine learning
2. Functional components: Mining of new functional components and directed evolution, activity regulation of high-performance catalytic components, combined with protein design technology to achieve more efficient catalysis 3. Regulation strategy: Using dynamic regulation methods based on biosensing technology and machine learning methods to achieve balanced distribution of metabolic flow and optimize regulation strategy
4. Target products: Biosynthesis of high value-added compounds such as bulk chemicals and food additives


Construction of microbial cell factories based on synthetic biotechnology, and biosynthesis of high-value compounds with carbon and nitrogen neutralization. By means of enzyme engineering, metabolic engineering and synthetic biology, combined with bioinformatics, machine learning and protein design technologies, the development of enabling technologies, the construction of artificial cell factories, the creation of high-performance catalytic components, and the dynamic regulation of metabolic pathways are carried out to achieve microbial refining of high value-added compounds and green biofabration. The research content includes but is not limited to:
1. Cell factory: Construction of artificial cell factory based on gene editing, high-throughput screening and omics technology, function optimization and prediction with the help of bioinformatics and machine learning
2. Functional components: Mining of new functional components and directed evolution, activity regulation of high-performance catalytic components, combined with protein design technology to achieve more efficient catalysis 3. Regulation strategy: Using dynamic regulation methods based on biosensing technology and machine learning methods to achieve balanced distribution of metabolic flow and optimize regulation strategy
4. Target products: Biosynthesis of high value-added compounds such as bulk chemicals and food additives

2010-2016, Tsinghua University, PhD
2006-2010, Beijing University of Chemical Technology, BA

2021-present, Pre-Appointed Assistant Professor, School of Life Sciences, Beijing Institute of Technology
2019-2020, University of Texas at Austin, Visiting Scholar, collaborator: Professor Hal Alper
2016-2021, Assistant Researcher, Institute of Agricultural Product Processing, Chinese Academy of Agricultural Sciences


2021-present, Pre-Appointed Assistant Professor, School of Life Sciences, Beijing Institute of Technology
2019-2020, University of Texas at Austin, Visiting Scholar, collaborator: Professor Hal Alper
2016-2021, Assistant Researcher, Institute of Agricultural Product Processing, Chinese Academy of Agricultural Sciences

1. Third Prize of the 9th Biology Competition for College Students in Beijing (2023)
2. The First Prize of "Qingjuqisi" Black Science and Technology Special Competition of "Qingjuqisi" 2023 "Challenge Cup" Capital College Students' Extracurricular Academic Science and Technology Works Competition in Beijing (2023)
3. The 18th "Challenge Cup" National College Students Extracurricular Academic Science and Technology Works Competition and the 20th "Century Cup" College Students Extracurricular Academic Science and Technology Works Competition University-level Grand Prize (2023)
4. The 18th "Challenge Cup" National Extra-Curricular Academic Science and Technology Works Competition for College Students and the 20th "Century Cup" Extra-curricular Academic Science and Technology Works Competition for College Students (2023)
5. University-level Silver Award of the 13th "Challenge Cup" Entrepreneurship Plan Competition for Chinese College Students (2022)
6. University-level Bronze Award of the 13th "Challenge Cup" Entrepreneurship Plan Competition for Chinese College Students (2022)
7. Beijing Institute of Technology 19th "Century Cup" Student Entrepreneurship Competition university-level Bronze Award twice (2022)
8. Two national projects of Innovation and Entrepreneurship Training Program for College students (2021,2022)
9. Four university-level projects of Innovation and Entrepreneurship Training Program for college students (2021,2022)

1. Third Prize of the 9th Biology Competition for College Students in Beijing (2023)
2. The First Prize of "Qingjuqisi" Black Science and Technology Special Competition of "Qingjuqisi" 2023 "Challenge Cup" Capital College Students' Extracurricular Academic Science and Technology Works Competition in Beijing (2023)
3. The 18th "Challenge Cup" National College Students Extracurricular Academic Science and Technology Works Competition and the 20th "Century Cup" College Students Extracurricular Academic Science and Technology Works Competition University-level Grand Prize (2023)
4. The 18th "Challenge Cup" National Extra-Curricular Academic Science and Technology Works Competition for College Students and the 20th "Century Cup" Extra-curricular Academic Science and Technology Works Competition for College Students (2023)
5. University-level Silver Award of the 13th "Challenge Cup" Entrepreneurship Plan Competition for Chinese College Students (2022)
6. University-level Bronze Award of the 13th "Challenge Cup" Entrepreneurship Plan Competition for Chinese College Students (2022)
7. Beijing Institute of Technology 19th "Century Cup" Student Entrepreneurship Competition university-level Bronze Award twice (2022)
8. Two national projects of Innovation and Entrepreneurship Training Program for College students (2021,2022)
9. Four university-level projects of Innovation and Entrepreneurship Training Program for college students (2021,2022)

1. Natural Science Foundation Project of Hebei Province, Metabolic Regulation Strategy Based on Amino acid Resource Allocation and its Application in Isobutanol Production (C2023105022), 2023/01-2025/12, Director
2. Beijing Natural Science Foundation Project, Dynamic and Precise Regulation of Biobase isobutyraldehyde Synthesis Process (2222026), 2022/01-2024/12, Host
3. Research on Efficient Microbial Synthesis of Amino acid Derivatives, Science and Technology Innovation Program, Beijing Institute of Technology, 2021/03-2024/06, Host
4. Youth Project of National Natural Science Foundation of China, vanillin synthetase Feruloyl-CoA Ligase (FCS) substrate Recognition and Catalytic Mechanism (31700701), 2018/01-2020/12, Host
5. Open Project of State Key Laboratory of Bioreactor Engineering, Identification and catalytic mechanism of Carotenoid cracking oxygenase CSO2 substrate (2018OPEN13), 2018/09-2020/08, Host