Calculated based on number of publications stored in Pure and citations from Scopus
20202024

Research activity per year

Personal profile

Personal profile



Associate Professor/Special Researcher (Doctoral Supervisor)
Contact us: xiaozy@bit.edu.cn
Recruitment direction: Stem Cell and Regenerative Medicine/Bioinformatics/Computer and Artificial Intelligence
Welcome students with single cell multi-omics/bioinformatics/Artificial intelligence background and research enthusiasm to join!
1. Education and Work experience
March 2022 - Present Researcher/Associate Professor, School of Life Sciences, Beijing Institute of Technology
August 2019 - March 2022 Special Research Assistant, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
August 2013 - June 2019 Ph.D., Molecular Cell Research Center, Leiden University Medical School, The Netherlands
Sep. 2009 - Jun. 2013 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences Master Sep. 2005 - Jul. 2009 Bachelor of Biotechnology, University of Science and Technology Beijing
2. Research field/direction
His main research areas include: developing new cutting-edge biotechnology methods such as single-cell multiomics, modified proteomics, and gene editing; Elucidation of molecular mechanisms that regulate cell fate and function during human physiology (maintenance, activation and differentiation of stem cells associated with early embryonic development) and disease (leukemia, tumorigenesis, progression); The digital map of the development of primate extra-embryonic tissue was systematically drawn. To construct new stem cells and mature functional cells. In the meantime,
Associate Professor/Special Researcher (Doctoral Supervisor)
Contact us: xiaozy@bit.edu.cn
Recruitment direction: Stem Cell and Regenerative Medicine/Bioinformatics/Computer and Artificial Intelligence
Welcome students with single cell multi-omics/bioinformatics/Artificial intelligence background and research enthusiasm to join!
1. Education and Work experience
March 2022 - Present Researcher/Associate Professor, School of Life Sciences, Beijing Institute of Technology
August 2019 - March 2022 Special Research Assistant, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
August 2013 - June 2019 Ph.D., Molecular Cell Research Center, Leiden University Medical School, The Netherlands
Sep. 2009 - Jun. 2013 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences Master Sep. 2005 - Jul. 2009 Bachelor of Biotechnology, University of Science and Technology Beijing
2. Research field/direction
His main research areas include: developing new cutting-edge biotechnology methods such as single-cell multiomics, modified proteomics, and gene editing; Elucidation of molecular mechanisms that regulate cell fate and function during human physiology (maintenance, activation and differentiation of stem cells associated with early embryonic development) and disease (leukemia, tumorigenesis, progression); The digital map of the development of primate extra-embryonic tissue was systematically drawn. To construct new stem cells and mature functional cells. In the meantime,

Research Interests



His main research areas include: developing new cutting-edge biotechnology methods such as single-cell multiomics, modified proteomics, and gene editing; Elucidation of molecular mechanisms that regulate cell fate and function during human physiology (maintenance, activation and differentiation of stem cells associated with early embryonic development) and disease (leukemia, tumorigenesis, progression); The digital map of the development of primate extra-embryonic tissue was systematically drawn. To construct new stem cells and mature functional cells. At the same time, Dr. Xiao Zhenyu pays close attention to the ethical, legal and national security issues in the frontier fields of stem cell and regenerative medicine, looks forward to the ethical challenges, social risks and rule conflicts brought by scientific development, and proposes a risk governance framework, with a view to promoting the good development of science and technology.
The details include:
1) Developing high-throughput single-cell multiomics, proteomics and modified omics analysis techniques;
2) To study the fate and function of human embryonic stem cells in vitro and in vivo and their ability to induce differentiation;
3) To analyze the signaling pathways and molecular mechanisms that regulate the fate of key intra - and extra-embryonic tissues in early embryonic development;
4) To establish the whole gestation time map of the differentiation of primate placenta from trophoectoderm to multiple trophoblast cell lineages;
5) To reveal the post-translational modification, targeted regulation and function of key proteins in the process of blood diseases and tumorigenesis.
6) Targeting DNA damage repair systems to improve the efficiency and accuracy of gene editing;
7) Elucidate the regulatory mechanisms of self-renewal and differentiation of trophoblast stem cells into syncytial trophoblast cells;

Education


March 2022 - Present Researcher/Associate Professor, School of Life Sciences, Beijing Institute of Technology
August 2019 - March 2022 Special Research Assistant, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
August 2013 - June 2019 Ph.D., Molecular Cell Research Center, Leiden University Medical School, The Netherlands
Sep. 2009 - Jun. 2013 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences Master Sep. 2005 - Jul. 2009 Bachelor of Biotechnology, University of Science and Technology Beijing

Professional Experience



March 2022 - Present Researcher/Associate Professor, School of Life Sciences, Beijing Institute of Technology
August 2019 - March 2022 Special Research Assistant, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
August 2013 - June 2019 Ph.D., Molecular Cell Research Center, Leiden University Medical School, The Netherlands
Sep. 2009 - Jun. 2013 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences Master Sep. 2005 - Jul. 2009 Bachelor of Biotechnology, University of Science and Technology Beijing


March 2022 - Present Researcher/Associate Professor, School of Life Sciences, Beijing Institute of Technology
August 2019 - March 2022 Special Research Assistant, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
August 2013 - June 2019 Ph.D., Molecular Cell Research Center, Leiden University Medical School, The Netherlands
Sep. 2009 - Jun. 2013 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences Master Sep. 2005 - Jul. 2009 Bachelor of Biotechnology, University of Science and Technology Beijing

Research Achievement


1) Marie Curie Upstream Network-Outstanding Fellow 2015 (EU Horizon Programme)
2) 2013 Outstanding Graduate of Institute of Zoology, Chinese Academy of Sciences
3) 2013-present: Marie Curie Fellow


1) Marie Curie Upstream Network-Outstanding Fellow 2015 (EU Horizon Programme)
2) 2013 Outstanding Graduate of Institute of Zoology, Chinese Academy of Sciences
3) 2013-present: Marie Curie Fellow


1) Host, National Natural Science Foundation Project, Study on the role and mechanism of INSL4 in the differentiation of Trophoblast cells in placental implantable Diseases, 2024.01-2027.12, 490,000 yuan, under research
2) Host, Beijing Institute of Technology Science and Technology Innovation Plan Original Foundation Frontier Intersection and Discipline Innovation Project, 2022.09-2024.09, 200,000 yuan, in research
3) Host, Beijing Institute of Technology Young Teachers Academic Start-up Program, 2022.09-2025.09, 600,000 yuan, in research
4) Host, National Natural Youth Science Foundation Project, Research on phosphorylated proteomics of Placental Trophoblast stem cells, 2021.1.1-2023.12, 240,000 yuan, under research
5) Host, Special Research Assistant Project of Chinese Academy of Sciences, Research on the Mechanism of Early Embryonic Development in Mice, 2019.08-2025.08, 600,000 yuan, under research
6) Host, "Zhiyi" postdoctoral Project, Research on the mechanism of Early Human Embryo Implantation, 2019.08-2022.08, 100,000 yuan, completed
7) Host, Young Jie Jun Research and Innovation Director Fund, Proteomics Research of Human Trophoblast Cell Fusion, 2020.08-20221.08, 50,000 yuan, completed
8) Chair, Marie Curie Foundation, The Role of SUMO Proteome in DNA Damage Repair, 2013.08-2019.06, 240,000 Euro, completed

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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