Advances in novel biosensors in biomedical applications

Axin Liang; Weidong Zhao; Tianjian Lv; Ziyu Zhu; Ruilin Haotian; Jiangjiang Zhang; Bingteng Xie; Yue Yi; Zikai Hao; Liquan Sun; Aiqin Luo

doi:10.1016/j.talanta.2024.126709

Advances in novel biosensors in biomedical applications

Axin Liang, Weidong Zhao, Tianjian Lv, Ziyu Zhu, Ruilin Haotian, Jiangjiang Zhang, Bingteng Xie, Yue Yi, Zikai Hao, Liquan Sun, Aiqin Luo^*

^*Corresponding author for this work

School of Life Science

Beijing Institute of Technology

Research output: Contribution to journal › Review article › peer-review

Abstract

Biosensors, devices capable of detecting biomolecules or bioactive substances, have recently become one of the important tools in the fields of bioanalysis and medical diagnostics. A biosensor is an analytical system composed of biosensitive elements and signal-processing elements used to detect various biological and chemical substances. Biomimetic elements are key to biosensor technology and are the components in a sensor that are responsible for identifying the target analyte. The construction methods and working principles of biosensors based on synthetic biomimetic elements, such as DNAzyme, molecular imprinted polymers and aptamers, and their updated applications in biomedical analysis are summarised. Finally, the technical bottlenecks and future development prospects for biomedical analysis are summarised and discussed.

Original language	English
Article number	126709
Journal	Talanta
Volume	280
DOIs	https://doi.org/10.1016/j.talanta.2024.126709
Publication status	Published - 1 Dec 2024

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title = "Advances in novel biosensors in biomedical applications",

abstract = "Biosensors, devices capable of detecting biomolecules or bioactive substances, have recently become one of the important tools in the fields of bioanalysis and medical diagnostics. A biosensor is an analytical system composed of biosensitive elements and signal-processing elements used to detect various biological and chemical substances. Biomimetic elements are key to biosensor technology and are the components in a sensor that are responsible for identifying the target analyte. The construction methods and working principles of biosensors based on synthetic biomimetic elements, such as DNAzyme, molecular imprinted polymers and aptamers, and their updated applications in biomedical analysis are summarised. Finally, the technical bottlenecks and future development prospects for biomedical analysis are summarised and discussed.",

author = "Axin Liang and Weidong Zhao and Tianjian Lv and Ziyu Zhu and Ruilin Haotian and Jiangjiang Zhang and Bingteng Xie and Yue Yi and Zikai Hao and Liquan Sun and Aiqin Luo",

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T1 - Advances in novel biosensors in biomedical applications

AU - Liang, Axin

AU - Zhao, Weidong

AU - Lv, Tianjian

AU - Zhu, Ziyu

AU - Haotian, Ruilin

AU - Zhang, Jiangjiang

AU - Xie, Bingteng

AU - Yi, Yue

AU - Hao, Zikai

AU - Sun, Liquan

AU - Luo, Aiqin

PY - 2024/12/1

Y1 - 2024/12/1

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AB - Biosensors, devices capable of detecting biomolecules or bioactive substances, have recently become one of the important tools in the fields of bioanalysis and medical diagnostics. A biosensor is an analytical system composed of biosensitive elements and signal-processing elements used to detect various biological and chemical substances. Biomimetic elements are key to biosensor technology and are the components in a sensor that are responsible for identifying the target analyte. The construction methods and working principles of biosensors based on synthetic biomimetic elements, such as DNAzyme, molecular imprinted polymers and aptamers, and their updated applications in biomedical analysis are summarised. Finally, the technical bottlenecks and future development prospects for biomedical analysis are summarised and discussed.

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DO - 10.1016/j.talanta.2024.126709

M3 - Review article

AN - SCOPUS:85201393635

SN - 0039-9140

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JO - Talanta

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Advances in novel biosensors in biomedical applications

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