Rapid identification and structural characterization of polyoxypregnane glycosides in Dregea sinensis by HPLC-MSn and HRMS

Juan Song, Fang Lv*, Rong Ji Dai, Yu Lin Deng

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

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摘要

By HPLC-MSn and HRMS analyses, the structures of 52 polyoxypregnane glycosides were rapidly inferred from Dregea sinensis Hemsl on the basis of their sodium-cationized molecules [M + Na]+ and predominant diagnostic ions resulting from the saccharic chain on C3 and the neutral loss of substituent on C11 and C12. Compounds 1 and 7 significantly inhibited LPS-stimulated splenocyte proliferation in vitro. (Figure presented.).

源语言英语
页(从-至)9-19
页数11
期刊Journal of Asian Natural Products Research
23
1
DOI
出版状态已出版 - 2021

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