Sharp-featured Au@Ag core/shell nanocuboid synthesis and the label-free ultrasensitive SERS detection of protein single-point mutations

Guopeng Tu, Ntirikwendera Deogratias, Meng Xu*, Xiaowei Li, Jiajia Liu, Lan Jiang, Yanlian Yang, Jiatao Zhang

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

7 引用 (Scopus)

摘要

Sharp-featured Au@Ag core/shell nanocuboids were synthesized. Simulation and experimental results demonstrated that the sharp features and in-cuboid, out-of-cuboid LSPR coupling of the nanocuboids enabled high SERS activities. The ultrasensitive detection of single-point mutations of TDP-43 proteins was demonstrated at 10 pM for the first time. This could be a general strategy for single-point mutation detection in proteins.

源语言英语
页(从-至)1720-1724
页数5
期刊Materials Chemistry Frontiers
2
9
DOI
出版状态已出版 - 9月 2018

指纹

探究 'Sharp-featured Au@Ag core/shell nanocuboid synthesis and the label-free ultrasensitive SERS detection of protein single-point mutations' 的科研主题。它们共同构成独一无二的指纹。

引用此