Stabilization of Grignard reagents by a pillar[5]arene host-Schlenk equilibria and Grignard reactions

Lingyi Shen; Yanxia Zhao; Dihua Dai; Ying Wei Yang; Biao Wu; Xiao Juan Yang

doi:10.1039/c9cc08728a

Stabilization of Grignard reagents by a pillar[5]arene host-Schlenk equilibria and Grignard reactions

Lingyi Shen, Yanxia Zhao, Dihua Dai, Ying Wei Yang^*, Biao Wu, Xiao Juan Yang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Grignard reagents (RMgX) are widely used in organic synthesis. However, these highly reactive compounds are supplied in inflammable solvents, which causes extra complexity in their transportation. Herein we report that Grignard reagents with linear alkyl chains can be entrapped and stabilized by the macrocyclic host pillar[5]arene while preserving their reactivity.

Original language	English
Pages (from-to)	1381-1384
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	9
DOIs	https://doi.org/10.1039/c9cc08728a
Publication status	Published - 2020
Externally published	Yes

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abstract = "Grignard reagents (RMgX) are widely used in organic synthesis. However, these highly reactive compounds are supplied in inflammable solvents, which causes extra complexity in their transportation. Herein we report that Grignard reagents with linear alkyl chains can be entrapped and stabilized by the macrocyclic host pillar[5]arene while preserving their reactivity.",

author = "Lingyi Shen and Yanxia Zhao and Dihua Dai and Yang, {Ying Wei} and Biao Wu and Yang, {Xiao Juan}",

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T1 - Stabilization of Grignard reagents by a pillar[5]arene host-Schlenk equilibria and Grignard reactions

AU - Shen, Lingyi

AU - Zhao, Yanxia

AU - Dai, Dihua

AU - Yang, Ying Wei

AU - Wu, Biao

AU - Yang, Xiao Juan

N1 - Publisher Copyright: This journal is © The Royal Society of Chemistry.

PY - 2020

Y1 - 2020

N2 - Grignard reagents (RMgX) are widely used in organic synthesis. However, these highly reactive compounds are supplied in inflammable solvents, which causes extra complexity in their transportation. Herein we report that Grignard reagents with linear alkyl chains can be entrapped and stabilized by the macrocyclic host pillar[5]arene while preserving their reactivity.

AB - Grignard reagents (RMgX) are widely used in organic synthesis. However, these highly reactive compounds are supplied in inflammable solvents, which causes extra complexity in their transportation. Herein we report that Grignard reagents with linear alkyl chains can be entrapped and stabilized by the macrocyclic host pillar[5]arene while preserving their reactivity.

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U2 - 10.1039/c9cc08728a

DO - 10.1039/c9cc08728a

M3 - Article

C2 - 31910250

AN - SCOPUS:85078693760

SN - 1359-7345

VL - 56

SP - 1381

EP - 1384

JO - Chemical Communications

JF - Chemical Communications

IS - 9

ER -

Stabilization of Grignard reagents by a pillar[5]arene host-Schlenk equilibria and Grignard reactions

Abstract

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