Polyhydroxyalkanoate/polyhydroxybutyrate

Ying Wang; Jinwei Dao; Guo Qiang Chen

doi:10.1016/B978-0-444-64046-8.00163-4

Polyhydroxyalkanoate/polyhydroxybutyrate

Ying Wang, Jinwei Dao, Guo Qiang Chen

School of Chemistry and Chemical Engineering

Tsinghua University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Polyhydroxyalkanoates (PHAs) are a diverse family of bacterially synthesized biopolyesters or bioplastics with biodegradability, biocompatibility, thermal processibilty and adjustable strengths. PHAs have been used to develop applications as bulk materials including films, articles, coating, fibers, foam materials, biofuels, chiral chemicals, medical implants and drug delivery carriers. Thanks to the next generation industrial biotechnology (NGIB), PHAs can be produced under open and continuous conditions to achieve economic competitiveness. Over the past years, NGIB combined with metabolic engineering and synthetic biology progresses very fast to produce successfully poly(3-hydroxybutyrate) (PHB), P3HB4HB copolymers of 3-hydroxybutyrate (3HB) and 4-hydroxybutyrate (4HB), PHBV of 3-hydroxybutyrate (HB) and 3-hydroxyvalerate (HV) in semi-industry scale. This chapter will describe major achievements in the PHA/PHB field.

Original language	English
Title of host publication	Comprehensive Biotechnology
Publisher	Elsevier
Pages	244-257
Number of pages	14
ISBN (Electronic)	9780444640475
ISBN (Print)	9780444640468
DOIs	https://doi.org/10.1016/B978-0-444-64046-8.00163-4
Publication status	Published - 1 Jan 2019

Keywords

Biocompatibility
Biofuel
Bioplastics
Biopolyesters
Implant materials
Metabolic engineering
Next generation industrial biotechnology
PHA
PHB
Polyhydroxalkanoates
Synthetic biology

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10.1016/B978-0-444-64046-8.00163-4

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title = "Polyhydroxyalkanoate/polyhydroxybutyrate",

abstract = "Polyhydroxyalkanoates (PHAs) are a diverse family of bacterially synthesized biopolyesters or bioplastics with biodegradability, biocompatibility, thermal processibilty and adjustable strengths. PHAs have been used to develop applications as bulk materials including films, articles, coating, fibers, foam materials, biofuels, chiral chemicals, medical implants and drug delivery carriers. Thanks to the next generation industrial biotechnology (NGIB), PHAs can be produced under open and continuous conditions to achieve economic competitiveness. Over the past years, NGIB combined with metabolic engineering and synthetic biology progresses very fast to produce successfully poly(3-hydroxybutyrate) (PHB), P3HB4HB copolymers of 3-hydroxybutyrate (3HB) and 4-hydroxybutyrate (4HB), PHBV of 3-hydroxybutyrate (HB) and 3-hydroxyvalerate (HV) in semi-industry scale. This chapter will describe major achievements in the PHA/PHB field.",

keywords = "Biocompatibility, Biofuel, Bioplastics, Biopolyesters, Implant materials, Metabolic engineering, Next generation industrial biotechnology, PHA, PHB, Polyhydroxalkanoates, Synthetic biology",

author = "Ying Wang and Jinwei Dao and Chen, {Guo Qiang}",

year = "2019",

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doi = "10.1016/B978-0-444-64046-8.00163-4",

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AU - Wang, Ying

AU - Dao, Jinwei

AU - Chen, Guo Qiang

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Polyhydroxyalkanoates (PHAs) are a diverse family of bacterially synthesized biopolyesters or bioplastics with biodegradability, biocompatibility, thermal processibilty and adjustable strengths. PHAs have been used to develop applications as bulk materials including films, articles, coating, fibers, foam materials, biofuels, chiral chemicals, medical implants and drug delivery carriers. Thanks to the next generation industrial biotechnology (NGIB), PHAs can be produced under open and continuous conditions to achieve economic competitiveness. Over the past years, NGIB combined with metabolic engineering and synthetic biology progresses very fast to produce successfully poly(3-hydroxybutyrate) (PHB), P3HB4HB copolymers of 3-hydroxybutyrate (3HB) and 4-hydroxybutyrate (4HB), PHBV of 3-hydroxybutyrate (HB) and 3-hydroxyvalerate (HV) in semi-industry scale. This chapter will describe major achievements in the PHA/PHB field.

AB - Polyhydroxyalkanoates (PHAs) are a diverse family of bacterially synthesized biopolyesters or bioplastics with biodegradability, biocompatibility, thermal processibilty and adjustable strengths. PHAs have been used to develop applications as bulk materials including films, articles, coating, fibers, foam materials, biofuels, chiral chemicals, medical implants and drug delivery carriers. Thanks to the next generation industrial biotechnology (NGIB), PHAs can be produced under open and continuous conditions to achieve economic competitiveness. Over the past years, NGIB combined with metabolic engineering and synthetic biology progresses very fast to produce successfully poly(3-hydroxybutyrate) (PHB), P3HB4HB copolymers of 3-hydroxybutyrate (3HB) and 4-hydroxybutyrate (4HB), PHBV of 3-hydroxybutyrate (HB) and 3-hydroxyvalerate (HV) in semi-industry scale. This chapter will describe major achievements in the PHA/PHB field.

KW - Biocompatibility

KW - Biofuel

KW - Bioplastics

KW - Biopolyesters

KW - Implant materials

KW - Metabolic engineering

KW - Next generation industrial biotechnology

KW - PHA

KW - PHB

KW - Polyhydroxalkanoates

KW - Synthetic biology

UR - http://www.scopus.com/inward/record.url?scp=85079540867&partnerID=8YFLogxK

U2 - 10.1016/B978-0-444-64046-8.00163-4

DO - 10.1016/B978-0-444-64046-8.00163-4

M3 - Chapter

AN - SCOPUS:85079540867

SN - 9780444640468

SP - 244

EP - 257

BT - Comprehensive Biotechnology

PB - Elsevier

ER -

Polyhydroxyalkanoate/polyhydroxybutyrate

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