Academic part-time job
Member of Molecular Microbiology and BioEngineering Committee of Chinese Society of Microbiology, Member of Youth Working Committee of Biochemical Engineering of Chinese Society of Chemical Engineering
Editor of Synthetic and Systems Biotechnology Journal
Editorial Member of Journal of BioEngineering
Editorial Board, Journal of Synthetic Biology
Honors
The 5th China Association for Science and Technology "Young Talent Lifting Project"
The 5th Min Eun-Taek Energy & Chemical Award Youth Progress Award

With the microbial synthesis of natural products, biological materials and other compounds as the research goal, change the traditional production mode, the use of metabolic engineering, synthetic biology, enzyme engineering and other means to build microbial cell factories, solve the key scientific problems of biosynthesis, improve production efficiency, aiming to achieve the above high value-added products of green biological manufacturing, promote industrial production. The main studies include:
1. Analyze the synthetic pathway of natural products in microorganisms, and realize the microbial synthesis of new compounds
2. Develop efficient gene assembly and genome editing technologies
3. Construction and regulation of metabolic pathways
4. Develop chassis cell modification technology for specific compounds to build efficient microbial cell factories
5. Microbial production of biomaterials

2010/09-2015/07: PhD, School of Life Sciences, Tsinghua University
2006/09-2010/06: Bachelor of Science, College of Life Sciences, Shandong University

2024/01-present: Associate Professor/Special Researcher, School of Chemistry and Chemical Engineering, Beijing Institute of Technology
2018/05-2023/12: Pre-Appointed Associate Professor/Special Researcher, School of Chemistry and Chemical Engineering, Beijing Institute of Technology 2016/10-2017/11: Postdoctoral Fellow, Department of Chemical Engineering, Massachusetts Institute of Technology, USA
2015/07-2018/04: Beijing Institute of Technology, Chemical Engineering and Technology, Postdoctoral Faculty

He presided over 4 national projects such as the National Natural Science Foundation and 2 sub-projects of the national key research and development Plan; Participated in the National Natural Science Foundation project, 973 project and other 4 projects. So far, he has published more than 30 academic papers in Metabolic Engineering, ACS Catalysis, Trends in Biotechnology, Biotechnology Advances and other high-level journals at home and abroad in this field. 5 authorized invention patents. Participated in the compilation and publication of the textbook of Synthetic Biology, and participated in the publication of 4 academic monographs.
Main Research Projects
1. Establishment of dynamic regulatory system of Escherichia coli tolerance to monoterpenes and enhancement of product synthesis, Project of National Natural Science Foundation of China, led by
2. Dose-effect Relationship and cooperative regulation of key enzymes in yeast triterpene synthesis, Project of National Natural Science Foundation of China, hosted by
3. Construction and application demonstration of microbial cell factory for synthetic plant natural products, National Key Research and Development Plan, sub-project leader
4. Platform technology for directional mining and efficient synthesis of new natural and artificial products, National Key Research and Development Plan, sub-project leader
5. China Association for Science and Technology "Young Talent Lifting Project", host
6. Extracellular transport and Synthetic Enhancement of Yeast Production of pentacyclic triterpenoids, National Natural Science Foundation of China (NSFC) 7. Beijing Institute of Technology Innovative Talents Special Plan Project, host
Representative Papers
1. Yu Yuan, Rasool Aamir, Liu Haoran, Lv Bo, Chang Pengcheng, Song Hao, Wang Ying*, Li Chun*. Engineering Saccharomyces cerevisiae for High Yield Production of α-amyrin via Synergistic Remodeling of. Li Chun*. Engineering Saccharomyces cerevisiae for high yield production of α-amyrin via synergistic remodeling of α-amyrin Synthase and Expanding the Storage Pool. Metabolic Engineering, 2020, 62:72-83 (IF=8.8)
2. Tan Dan#, Wang Ying#, Tong Yi, Chen Guo-Qiang*. Grand Challenges for Industrializing Polyhydroxyalkanoates (PHAs), Trends in Biotechnology, 2021, 39:953-963 (ESI highly cited papers, IF=21.9)
3. Sun Wentao, Xue Haijie, Liu Hu, Lv Bo, Yu Yang*, Wang Ying*, Huang Meilan, Li Chun*. Controlling Chemo- and Regioselectivity of a Plant P450 in Yeast Cell toward Rare Licorice Triterpenoid Biosynthesis, ACS Catalysis, 2020, 10: 4253-4260 (IF=13.7)
4. Zhu Ying, Zhou Chen, Liu Xia, Li Xinying, Shi Caifang, Zhang Yapeng, Wang Ying*, Li Chun*. Aided‐efflux and high production of β‐amyrin realized by β‐cyclodextrin in situ synthesized on surface of Saccharomyces cerevisiae, Biotechnology and Bioengineering, 2023, 120:1147-1158 (IF=4.4)
5. Wang Ying, Ling Chen, Chen Yong, Jiang Xiaoran, Chen Guo-Qiang *. Microbial engineering for easy downstream processing. Biotechnology Advances, 2019, 37: 107365 (IF=17.7)
6. Zhang Xu, Lin Yina, Wu Qiong, Wang Ying*, Chen Guo-Qiang*. Synthetic Biology and Genome Editing Tools for Improving PHA Metabolic Engineering, Trends in Biotechnology, 2019, 38: 689-700 (IF=21.9)
7. Li Chenyi#, Gao Xiaopeng#, Peng Xiao, Li Jinlin, Bai Wenxin, Zhong Jiadong, He Mengchao, Xu Ke, Wang Ying*, Li Chun*, Intelligent microbial cell factory with genetic pH shooting (GPS) for cell selfresponsive base/acid regulation. Microbial Cell Factories, 2020, 19:202 (IF=6.4)
8. Luo Yan, Jiang Yaozhu, Chen Linhao, Li Chun, Wang Ying*. Applications of protein engineering in the microbial synthesis of plant triterpenoids. Synthetic and Systems Biotechnology, 2023, 8:20-32 (IF=4.7)
9. Zhu Ying, Zhou Chen, Wang Ying*, Li Chun*, Transporter Engineering for Microbial Manufacturing. Biotechnology Journal, 2020, 15, 1900494 (IF=5.7)
10. Alkhadrawi Adham M., Wang Ying*, Li Chun*. In-silico screening of potential target transporters for glycyrrhetinic acid (GA) via deep learning prediction of drug-target interactions. Biochemical Engineering Journal, 2022, 181:108375 (IF=4.4)
11. Jia Nan#, Li Jingzhi#, Zang Guowei, Yu Yuan, Jin Xiaojv, He Yuna, Feng Meilin, Na Xuemei, Wang Ying*, Li Chun*. Engineering Saccharomyces cerevisiae for high-efficient production of ursolic acid via cofactor engineering and acetyl-CoA optimization. Biochemical Engineering Journal, 2024, 109189. (IF=4.4)
12. Li Jinling#, Wang Shuai#, Miao Yinan, Wan Ya, Li Chun*, Wang Ying*. Mining and modification of Oryza sativa-derived squalene epoxidase for improved β-amyrin production in China Journal of Biotechnology, 2023, 375:1-11 (IF=4.1)
13. Wang Ying#, Chung Ahleum#, Chen Guo-Qiang*. Synthesis of medium-chain-length polyhydroxyalkanoate homopolymers, random copolymers, and block copolymers by an engineered strain of Pseudomonas entomophila. Advanced Healthcare Materials, 2017, 6: 1601017 (IF=11.1)
14. Wang Ying, Wu Hong, Jiang Xiaoran, Chen Guo-Qiang*. Engineering Escherichia coli for enhanced production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in larger cellular space. Metabolic Engineering, 2014, 25: 183-193 (IF=8.8)
15. Wang Ying#, Li Yan#, Xua Tuan, Shi Zhenyu*, Wu Qiong*. Experimental evidence for growth advantage and metabolic shift stimulated by photophosphorylation of proteorhodopsin expressed in Escherichia coli at anaerobic condition. Biotechnology and Bioengineering, 2015, 112: 947-956 (IF=4.4)