Because I like to communicate with students, the three-foot platform has always been my work passion, and I enjoy the interaction between teachers and students and the pleasant process of "teaching and learning" every semester. The textbook "Synthetic Biology" published as the deputy editor won the Excellent Publication Award of China Petroleum and Chemical Industry (the first prize of the textbook Award). Daily responsible for the "Synthetic Biology Club" for all undergraduates, held the club's publicity and recruitment, and encouraged the undergraduate team to actively participate in the "iGem International Genetic Machine Competition", "Internet +", "Challenge Cup" and other innovation and entrepreneurship competitions; Presided over the construction of Beijing's double-first-class international cooperation joint laboratory "BIT-QUB iSynBio Lab", and explored a cooperation platform for international cultivation of biochemistry. In terms of scientific research, the engineering ideas of synthetic biology are mainly used to reprogram the genome of microbial cells, establish new methods, obtain new strains, effectively improve product yield and reduce production costs, and the future promotion of industry, university and research will also effectively improve the technical level of enterprises and social and economic benefits. Among them, Published as the corresponding author of "Simultaneously down-regulation of multiplex branch pathways using CRISPRi and fermentation optimization for Fermentation. enhancing β-amyrin production in Saccharomyces cerevisiae "was awarded by the academic journal Synthetic and Systems Biotechnology The top 10 most-cited papers of 2019-2020.

His research field is synthetic biology. 1. Intelligent manufacturing and fine regulation of microbial cell factories: building a variety of industrial strain platforms including Saccharomyces cerevisiae for efficient production of fuel ethanol, medicinal natural products and medicinal proteins; 2. Improve cell physiology, production performance and automatic response to environment by constructing standardized component libraries, genome editing and high-throughput omics analysis and other synthetic biology techniques; 3. Establish cancer targeted therapy technology to achieve accurate design and engineering application of anti-tumor pharmaceutical molecules.

2000.09-2005.07 PhD, School of Life Sciences, Peking University
1996.09-2000.07 Bachelor of Science, College of Life Sciences, Beijing Normal University

2017.12-present Associate Professor, School of Chemistry and Chemical Engineering, Beijing Institute of Technology
2014.06-2017.11 Associate Professor, School of Life Sciences, Beijing Institute of Technology
2005.08-2013.05 Postdoctoral and Research Assistant, Cancer Center, University of Pittsburgh, USA

He presided over 2 projects of the National Natural Science Foundation, 1 project of "synthetic biology" and 1 project of "green biological manufacturing" of the national key research and development plan, and 1 project of enterprise cooperation. Published 20 SCI/EI papers. 1 national authorized patent.
1. CRISPR/Cas9 genome editing technology was used to achieve finely regulated engineering yeast cell factories, and high-yield engineering strains of various medicinal natural products such as beta-amyrin and glycyrrhetinic acid GA were successfully constructed.
2. The intelligent response environment system of yeast cells was built through gene circuit design, directed evolution and other methods, which effectively improved the green bio-manufacturing capability of clean energy fuel ethanol.
3. Designed and developed a cancer targeted molecular therapy technology mediated by cytokine Chemokines to effectively regulate the immune microenvironment in the tumor region, and has achieved clinical (phase I) experiments in the United States.