TY - JOUR
T1 - Correlated evolution of social organization and lifespan in mammals
AU - Zhu, Pingfen
AU - Liu, Weiqiang
AU - Zhang, Xiaoxiao
AU - Li, Meng
AU - Liu, Gaoming
AU - Yu, Yang
AU - Li, Zihao
AU - Li, Xuanjing
AU - Du, Juan
AU - Wang, Xiao
AU - Grueter, Cyril C.
AU - Li, Ming
AU - Zhou, Xuming
N1 - Publisher Copyright:
© 2023, The Author(s).
PY - 2023/12
Y1 - 2023/12
N2 - Discerning the relationship between sociality and longevity would permit a deeper understanding of how animal life history evolved. Here, we perform a phylogenetic comparative analysis of ~1000 mammalian species on three states of social organization (solitary, pair-living, and group-living) and longevity. We show that group-living species generally live longer than solitary species, and that the transition rate from a short-lived state to a long-lived state is higher in group-living than non-group-living species, altogether supporting the correlated evolution of social organization and longevity. The comparative brain transcriptomes of 94 mammalian species identify 31 genes, hormones and immunity-related pathways broadly involved in the association between social organization and longevity. Further selection features reveal twenty overlapping pathways under selection for both social organization and longevity. These results underscore a molecular basis for the influence of the social organization on longevity.
AB - Discerning the relationship between sociality and longevity would permit a deeper understanding of how animal life history evolved. Here, we perform a phylogenetic comparative analysis of ~1000 mammalian species on three states of social organization (solitary, pair-living, and group-living) and longevity. We show that group-living species generally live longer than solitary species, and that the transition rate from a short-lived state to a long-lived state is higher in group-living than non-group-living species, altogether supporting the correlated evolution of social organization and longevity. The comparative brain transcriptomes of 94 mammalian species identify 31 genes, hormones and immunity-related pathways broadly involved in the association between social organization and longevity. Further selection features reveal twenty overlapping pathways under selection for both social organization and longevity. These results underscore a molecular basis for the influence of the social organization on longevity.
UR - http://www.scopus.com/inward/record.url?scp=85147170042&partnerID=8YFLogxK
U2 - 10.1038/s41467-023-35869-7
DO - 10.1038/s41467-023-35869-7
M3 - Article
C2 - 36720880
AN - SCOPUS:85147170042
SN - 2041-1723
VL - 14
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 372
ER -