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Computational design of variants for cephalosporin C acylase from Pseudomonas strain N176 with improved stability and activity
Ye Tian
, Xiaoqiang Huang, Qing Li, Yushan Zhu
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此作品的通讯作者
Tsinghua University
科研成果
:
期刊稿件
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同行评审
25
引用 (Scopus)
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Biochemistry, Genetics and Molecular Biology
Active Site
100%
Amidohydrolase
100%
Pseudomonas
100%
Catalytic Efficiency
50%
Point Mutation
50%
Melting Temperature
50%
Enzyme
25%
Intrinsic Clearance
25%
Industrial Scale
25%
Pharmacology, Toxicology and Pharmaceutical Science
Amidase
100%
Cephalosporin C
100%
Pseudomonas
100%
Intrinsic Clearance
25%
7 Aminocephalosporanic Acid
25%
Chemistry
Cephalosporin C
100%
Melting Point
50%
Intrinsic Clearance
25%
Engineering
Improvement Activity
25%