Tetraphenylethylene sulfonate derivative as turn-on fluorescent sensor for berberine chloride detection in aqueous solution

Han Jun Huang; Si Yu Gao; Ai Juan Zhao; Wittaya Ngeontae; Han Chun Wu; Fu Min Wang; Xiang Kui Ren

doi:10.1016/j.jpba.2022.115030

Tetraphenylethylene sulfonate derivative as turn-on fluorescent sensor for berberine chloride detection in aqueous solution

Han Jun Huang, Si Yu Gao, Ai Juan Zhao, Wittaya Ngeontae, Han Chun Wu, Fu Min Wang^*, Xiang Kui Ren^*

^*Corresponding author for this work

School of Physics

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A negatively-charged tetraphenylethylene derivative (TPE-SE) was designed and synthesized as turn-on fluorescent sensor for berberine chloride (BBC) detection in aqueous solution. The fluorescent property and detection mechanism were elucidated by UV–vis absorption spectra, photoluminescence spectra, dynamic light scattering experiments. The results reveal that the BBC can lead to aggregation-induced emission of TPE-SE due to the electrostatic interactions, endowing TPE-SE with excellent turn-on detecting ability, high selectivity and sensitivity to BBC. The detection limit is as low as 6.58 × 10⁻⁶M. These results should be applicable to fabricate special turn-on fluorescent sensors towards various antibiotics, and it is crucially important for achieving reasonable control and intake of small biomolecules.

Original language	English
Article number	115030
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	220
DOIs	https://doi.org/10.1016/j.jpba.2022.115030
Publication status	Published - 25 Oct 2022

Keywords

Aggregation-induced emission
Berberine chloride
Fluorescence sensor
Tetraphenylethylene
Turn-on

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10.1016/j.jpba.2022.115030

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title = "Tetraphenylethylene sulfonate derivative as turn-on fluorescent sensor for berberine chloride detection in aqueous solution",

abstract = "A negatively-charged tetraphenylethylene derivative (TPE-SE) was designed and synthesized as turn-on fluorescent sensor for berberine chloride (BBC) detection in aqueous solution. The fluorescent property and detection mechanism were elucidated by UV–vis absorption spectra, photoluminescence spectra, dynamic light scattering experiments. The results reveal that the BBC can lead to aggregation-induced emission of TPE-SE due to the electrostatic interactions, endowing TPE-SE with excellent turn-on detecting ability, high selectivity and sensitivity to BBC. The detection limit is as low as 6.58 × 10−6M. These results should be applicable to fabricate special turn-on fluorescent sensors towards various antibiotics, and it is crucially important for achieving reasonable control and intake of small biomolecules.",

keywords = "Aggregation-induced emission, Berberine chloride, Fluorescence sensor, Tetraphenylethylene, Turn-on",

author = "Huang, {Han Jun} and Gao, {Si Yu} and Zhao, {Ai Juan} and Wittaya Ngeontae and Wu, {Han Chun} and Wang, {Fu Min} and Ren, {Xiang Kui}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

year = "2022",

month = oct,

day = "25",

doi = "10.1016/j.jpba.2022.115030",

language = "English",

volume = "220",

journal = "Journal of Pharmaceutical and Biomedical Analysis",

issn = "0731-7085",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Tetraphenylethylene sulfonate derivative as turn-on fluorescent sensor for berberine chloride detection in aqueous solution

AU - Huang, Han Jun

AU - Gao, Si Yu

AU - Zhao, Ai Juan

AU - Ngeontae, Wittaya

AU - Wu, Han Chun

AU - Wang, Fu Min

AU - Ren, Xiang Kui

PY - 2022/10/25

Y1 - 2022/10/25

N2 - A negatively-charged tetraphenylethylene derivative (TPE-SE) was designed and synthesized as turn-on fluorescent sensor for berberine chloride (BBC) detection in aqueous solution. The fluorescent property and detection mechanism were elucidated by UV–vis absorption spectra, photoluminescence spectra, dynamic light scattering experiments. The results reveal that the BBC can lead to aggregation-induced emission of TPE-SE due to the electrostatic interactions, endowing TPE-SE with excellent turn-on detecting ability, high selectivity and sensitivity to BBC. The detection limit is as low as 6.58 × 10−6M. These results should be applicable to fabricate special turn-on fluorescent sensors towards various antibiotics, and it is crucially important for achieving reasonable control and intake of small biomolecules.

AB - A negatively-charged tetraphenylethylene derivative (TPE-SE) was designed and synthesized as turn-on fluorescent sensor for berberine chloride (BBC) detection in aqueous solution. The fluorescent property and detection mechanism were elucidated by UV–vis absorption spectra, photoluminescence spectra, dynamic light scattering experiments. The results reveal that the BBC can lead to aggregation-induced emission of TPE-SE due to the electrostatic interactions, endowing TPE-SE with excellent turn-on detecting ability, high selectivity and sensitivity to BBC. The detection limit is as low as 6.58 × 10−6M. These results should be applicable to fabricate special turn-on fluorescent sensors towards various antibiotics, and it is crucially important for achieving reasonable control and intake of small biomolecules.

KW - Aggregation-induced emission

KW - Berberine chloride

KW - Fluorescence sensor

KW - Tetraphenylethylene

KW - Turn-on

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U2 - 10.1016/j.jpba.2022.115030

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SN - 0731-7085

VL - 220

JO - Journal of Pharmaceutical and Biomedical Analysis

JF - Journal of Pharmaceutical and Biomedical Analysis

M1 - 115030

ER -

Tetraphenylethylene sulfonate derivative as turn-on fluorescent sensor for berberine chloride detection in aqueous solution

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Keywords

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