A series of pyrido[2,3-b[pyrazin-3(4 H)-one derivatives as aldose reductase inhibitors with antioxidant activity

Biochemistry, Genetics and Molecular Biology

• IC50 100%
• Antioxidant Activity 100%
• Aldose Reductase Inhibitor 100%
• Docking (Molecular) 50%
• Structure Activity Relation 50%
• Enzyme 50%
• Acetic Acid 50%
• Oxidative Stress 50%
• Trolox 50%
• Aldose Reductase 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Antioxidant Capacity 100%
• Antioxidant 100%
• Aldose Reductase Inhibitor 100%
• Phenazone 100%
• IC50 66%
• Diabetic Complication 33%
• Structure Activity Relationship 33%
• Potassium Acetate 33%
• Aldehyde Reductase 33%
• Trolox C 33%

Chemistry

• Antioxidant Agent 100%
• Antioxidant Capacity 100%
• Aldose Reductase Inhibitor 100%
• Hydroxyl 66%
• IC50 66%
• Acetic Acid 33%
• Structure-Activity Relationship 33%
• % Inhibition 33%
• Oxidative Stress 33%
• Trolox 33%
• Aldose 33%