He has more than 20 years of work experience in universities and nearly 30 years of practical experience in drug research, and loves teaching and scientific research. In recent years, we have cooperated with pharmaceutical companies and committed to the research of therapeutic drugs for metabolic diseases and malignant tumors that threaten human health

The research field mainly focuses on the prevention and treatment of diabetes complications and tumor immunotherapy, and is committed to providing new drugs and methods for the prevention and treatment of these major diseases that threaten human health. Specific research directions: 1. Research and development of lead compounds for the prevention and treatment of diabetes complications, mainly focusing on the design, synthesis and activity study of inhibitors of aldose reductase, an important enzyme in glucose metabolism. 2. Design, screening and pharmacological and toxicological research of targeted nano polypeptide drugs for tumor immunotherapy. 3. Research on nanodrug delivery system.

2000.08-2003.07 Peking University Health Science Center, Pharmacology, MD
1993.08-1996.07 Master of Science in Pharmacology, Shenyang Pharmaceutical University 1989.09-1993.07 Shenyang Pharmaceutical University, Major in Pharmaceutical Preparations, Bachelor of Engineering

2016.08-present Associate Professor, Master Supervisor, School of Chemistry and Chemical Engineering, Beijing Institute of Technology
2005.12-2016.07 School of Chemical Engineering and Environment, Beijing Institute of Technology, Lecturer, Associate Professor, Master Tutor 1996.08-2000.08 Assistant and Lecturer, Department of Pharmacology, School of Basic Medicine, Peking University Health Science Center

Over the years, we have focused on the research and development of novel aldose reductase inhibitors, and to date, nearly 400 structurally novel compounds have been synthesized, and nearly 10 promising drug candidates have been developed through in vivo activity studies. There are several high-level papers published in top or important journals in the field, such as Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Bioorganic and Medicinal Chemistry, ChemMedChem, Chemistry Select, etc. Good results have also been achieved in the RESEARCH of anti-tumor targeting nanopeptides and nanodrug delivery systems, and papers have been published in ACS NANO, NANO RESEARCH and other journals. The research was supported by the National Natural Science Foundation of China and the Natural Science Foundation of Beijing.