Research output per year
Research output per year
Personal profile
Research Interests
At present, the main research direction of our research group is the regulation of RNA-mediated gene expression in bacteria, especially the regulation mechanism of pathogenic gene expression. The molecular mechanism of gene expression regulation at the RNA level was elucidate by means of biochemistry, structural biology and microbiology, providing theoretical basis and new ideas for the treatment of related diseases.
At present, the main research direction of our research group is the regulation of RNA-mediated gene expression in bacteria, especially the regulation mechanism of pathogenic gene expression. The molecular mechanism of gene expression regulation at the RNA level was elucidate by means of biochemistry, structural biology and microbiology, providing theoretical basis and new ideas for the treatment of related diseases.
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Dive into the research topics where Ang Gao is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Molecular basis of SLC19A1-mediated folate and cyclic dinucleotide transport
Zhang, Q., Zhang, X., Liu, K., Zhu, Y., Nie, X., Ma, J., Sun, P., Li, Z., Gao, Y., Liu, S., Gao, A., Zhang, L. & Gao, P., Dec 2025, In: Nature Communications. 16, 1, 3146.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion
Huang, J., Zhu, K., Gao, Y., Ye, F., Li, Z., Ge, Y., Liu, S., Yang, J. & Gao, A., Dec 2024, In: Nature Communications. 15, 1, 3954.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Recognition of cyclic dinucleotides and folates by human SLC19A1
Zhang, Q., Zhang, X., Zhu, Y., Sun, P., Zhang, L., Ma, J., Zhang, Y., Zeng, L., Nie, X., Gao, Y., Li, Z., Liu, S., Lou, J., Gao, A., Zhang, L. & Gao, P., 1 Dec 2022, In: Nature. 612, 7938, p. 170-176 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH
Gao, A., Vasilyev, N., Kaushik, A., Duan, W. & Serganov, A., 2021, In: Nucleic Acids Research. 48, 7, p. 3776-3788 13 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
Zhu, Y., Gao, A., Zhan, Q., Wang, Y., Feng, H., Liu, S., Gao, G., Serganov, A. & Gao, P., 18 Apr 2019, In: Molecular Cell. 74, 2, p. 296-309.e7Research output: Contribution to journal › Article › peer-review
Open Access86 Citations (Scopus)