Synthesis of 2-aroyl-(4 or 5)-aryl-1H-imidazoles and 2-hydroxy-3,6-diaryl- pyrazines via a cascade process

Cong Liu, Rong J. Dai*, Guo W. Yao, Yu L. Deng

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

8 引用 (Scopus)

摘要

The synthesis of (4 or 5)-aryl-2-aroyl-1H-imidazoles and 2-hydroxy-3,6-diarylpyrazines from aryl methyl ketones via a cascade process of DMSO-HBr oxidation and Debus reaction was investigated. Owing to the simple starting materials, mild conditions, easy operation, high bioactivity of imidazole and pyrazine derivatives, this protocol has great potential in medicinal chemistry.

源语言英语
页(从-至)146-163
页数18
期刊Arkivoc
2014
4
DOI
出版状态已出版 - 25 2月 2014

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