摘要
A series of novel 2′,3′-dideoxy-2′,3′-diethanethioribonucleosides and those modified with a triazole ring were prepared in excellent yields and their antitumor activity was evaluated. Nucleosides with a triazole ring, 16a-16c, showed significantly improved activity towards a broad range of tumor cell lines.
| 源语言 | 英语 |
|---|---|
| 页（从-至） | 240-243 |
| 页数 | 4 |
| 期刊 | Bioorganic and Medicinal Chemistry Letters |
| 卷 | 20 |
| 期 | 1 |
| DOI | |
| 出版状态 | 已出版 - 1 1月 2010 |
指纹
探究 'Synthesis and antitumor activity of novel 2′,3′-dideoxy-2′,3′-diethanethionucleosides bearing 1,2,3-triazole residues' 的科研主题。它们共同构成独一无二的指纹。引用此
Yu, J. L., Wu, Q. P., Zhang, Q. S., Liu, Y. H., Li, Y. Z., & Zhou, Z. M. (2010). Synthesis and antitumor activity of novel 2′,3′-dideoxy-2′,3′-diethanethionucleosides bearing 1,2,3-triazole residues. Bioorganic and Medicinal Chemistry Letters, 20(1), 240-243. https://doi.org/10.1016/j.bmcl.2009.10.127