Surface plasmon resonance sensor combining with molecularly imprinted film for progesterone detection

Qing Wen Zhang; Ya Min Ren; Tian Xin Wei

doi:10.15918/j.tbit1001-0645.2015.02.019

Surface plasmon resonance sensor combining with molecularly imprinted film for progesterone detection

Qing Wen Zhang, Ya Min Ren, Tian Xin Wei^*

^*此作品的通讯作者

化学与化工学院

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

A surface plasmon resonance (SPR) sensor based on molecularly imprinted film (MIF) was proposed for the sensitive detection of progesterone. The MIF was synthesized by the method of thermo and photo polymerization on the sensor surface, which was subsequently removed to form the recognition cavities by the mixture of acetonitrile and acetic acid. The SPR sensor develops the angle shift by 1.15° (thermo polymerization) and 0.72° (photo polymerization) after washing progesterone from MIF and allowed detection of progesterone at concentration down to 10^-14 g/mL. The resonance angle changes show a good linearity versus minus logarithmic concentration of progesterone from 10^-14 g/mL to 10^-6 g/mL. A control experiment with the analogues estradiol, testosterone and testosterone propionate (10^-4 g/mL) shows a good selectivity of the MIF for the recognition of progesterone.

源语言	英语
页（从-至）	208-212
页数	5
期刊	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
卷	35
期	2
DOI	https://doi.org/10.15918/j.tbit1001-0645.2015.02.019
出版状态	已出版 - 1 2月 2015

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title = "Surface plasmon resonance sensor combining with molecularly imprinted film for progesterone detection",

abstract = "A surface plasmon resonance (SPR) sensor based on molecularly imprinted film (MIF) was proposed for the sensitive detection of progesterone. The MIF was synthesized by the method of thermo and photo polymerization on the sensor surface, which was subsequently removed to form the recognition cavities by the mixture of acetonitrile and acetic acid. The SPR sensor develops the angle shift by 1.15° (thermo polymerization) and 0.72° (photo polymerization) after washing progesterone from MIF and allowed detection of progesterone at concentration down to 10-14 g/mL. The resonance angle changes show a good linearity versus minus logarithmic concentration of progesterone from 10-14 g/mL to 10-6 g/mL. A control experiment with the analogues estradiol, testosterone and testosterone propionate (10-4 g/mL) shows a good selectivity of the MIF for the recognition of progesterone.",

keywords = "Molecularly imprinted film (MIF), Progesterone, Surface plasmon resonance (SPR)",

author = "Zhang, {Qing Wen} and Ren, {Ya Min} and Wei, {Tian Xin}",

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AU - Zhang, Qing Wen

AU - Ren, Ya Min

AU - Wei, Tian Xin

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N2 - A surface plasmon resonance (SPR) sensor based on molecularly imprinted film (MIF) was proposed for the sensitive detection of progesterone. The MIF was synthesized by the method of thermo and photo polymerization on the sensor surface, which was subsequently removed to form the recognition cavities by the mixture of acetonitrile and acetic acid. The SPR sensor develops the angle shift by 1.15° (thermo polymerization) and 0.72° (photo polymerization) after washing progesterone from MIF and allowed detection of progesterone at concentration down to 10-14 g/mL. The resonance angle changes show a good linearity versus minus logarithmic concentration of progesterone from 10-14 g/mL to 10-6 g/mL. A control experiment with the analogues estradiol, testosterone and testosterone propionate (10-4 g/mL) shows a good selectivity of the MIF for the recognition of progesterone.

AB - A surface plasmon resonance (SPR) sensor based on molecularly imprinted film (MIF) was proposed for the sensitive detection of progesterone. The MIF was synthesized by the method of thermo and photo polymerization on the sensor surface, which was subsequently removed to form the recognition cavities by the mixture of acetonitrile and acetic acid. The SPR sensor develops the angle shift by 1.15° (thermo polymerization) and 0.72° (photo polymerization) after washing progesterone from MIF and allowed detection of progesterone at concentration down to 10-14 g/mL. The resonance angle changes show a good linearity versus minus logarithmic concentration of progesterone from 10-14 g/mL to 10-6 g/mL. A control experiment with the analogues estradiol, testosterone and testosterone propionate (10-4 g/mL) shows a good selectivity of the MIF for the recognition of progesterone.

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Surface plasmon resonance sensor combining with molecularly imprinted film for progesterone detection

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