Study on HPCE enantiomeric separation of two drug racemates

Fang Li*, Hui Jin, Junling Gu, Ruonong Fu, Rongji Dai

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

1 引用 (Scopus)

摘要

It was reported for the first time that the racemic ofloxacin and 2-amino-N-isobutyl-l-phenylethanol enantiomers were separated by HPCE. The effects of the important experimental parameters such as the concentration of the chiral selector and pH of the background electrolyte on the separations were investigated. And the baseline separation of enantiomers of ofloxacin and 2-amino-N-isobutyl-1-phenylethanol was finally achieved with CZE using 2, 6-dimethyl-β-CD as the chiral selector.

源语言英语
页(从-至)166-169
页数4
期刊Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
17
2
出版状态已出版 - 1997

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