TY - JOUR
T1 - Simulation study on the mass transport in PCL based on the ciliated dynamic system of the respiratory tract
AU - Zhu, Pengfei
AU - Chen, Duanduan
AU - Xu, Yuanqing
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2019/8/21
Y1 - 2019/8/21
N2 - In this paper, a two-dimensional dynamic model of human respiratory cilia is established by immersed boundary-lattice Boltzmann method. In the model, periciliary liquid and mucus layer with different flow characteristics are considered, in which the non-Newtonian fluid in the viscous layer is described by Oldroyd-B model; the area between two layers is dynamically divided by a virtual membrane. By changing the cilium beat amplitude and the depth of periciliary liquid, this paper focuses on the removal of particle impurities by cilium beat. The results show that when the initial position is near the top of cilium, the particle tends to migrate upward to approach the mucus layer. However, if the initial position is near the middle or at lower part of the cilia, most of the particles will not be transferred to the vicinity of mucus layer by the swinging cilium. It is also found that by increasing the beat amplitude of cilia, particles are more likely to approach the mucus layer. By conducting this study, the migration of the particle in periciliary liquid is discussed in detail. The results are significant to help us to know the material transport law of human respiratory tract.
AB - In this paper, a two-dimensional dynamic model of human respiratory cilia is established by immersed boundary-lattice Boltzmann method. In the model, periciliary liquid and mucus layer with different flow characteristics are considered, in which the non-Newtonian fluid in the viscous layer is described by Oldroyd-B model; the area between two layers is dynamically divided by a virtual membrane. By changing the cilium beat amplitude and the depth of periciliary liquid, this paper focuses on the removal of particle impurities by cilium beat. The results show that when the initial position is near the top of cilium, the particle tends to migrate upward to approach the mucus layer. However, if the initial position is near the middle or at lower part of the cilia, most of the particles will not be transferred to the vicinity of mucus layer by the swinging cilium. It is also found that by increasing the beat amplitude of cilia, particles are more likely to approach the mucus layer. By conducting this study, the migration of the particle in periciliary liquid is discussed in detail. The results are significant to help us to know the material transport law of human respiratory tract.
KW - Oldroyd-B model
KW - cilium beat
KW - human respiratory tract
KW - immersed boundary-lattice Boltzmann method
KW - particle migration
UR - http://www.scopus.com/inward/record.url?scp=85072126242&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1300/1/012068
DO - 10.1088/1742-6596/1300/1/012068
M3 - Conference article
AN - SCOPUS:85072126242
SN - 1742-6588
VL - 1300
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012068
T2 - 2019 3rd International Conference on Fluid Mechanics and Industrial Applications, FMIA 2019
Y2 - 29 June 2019 through 30 June 2019
ER -