Palladium-Catalyzed Intramolecular Decarboxylative Allylic Amination of Aroyloxycarbamates

Allylamine compounds are one of the important compounds in organic synthetic chemistry and pharmaceutical chemistry, the synthetic methods of which are concerned. Using aroyloxycarbamates as start material, which was prepared in situ by cheap and easy-available carboxylic acid and hydroxylamine, allylamine compounds were synthesized by decarboxylation in one step. The reaction conditions are mild and the substrate is generally applicable. Moreover, the reaction realized the synthesis of indole.