Morita–Baylis–Hillman adducts as effective dipolarophiles in Copper(i)-catalyzed 1,3-dipolar cycloaddition with azomethine ylides: Asymmetric construction of pyrrolidine derivatives containing quaternary stereogenic center

Huai Long Teng, He Huang, Hai Yan Tao, Chun Jiang Wang*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

47 引用 (Scopus)

摘要

The first catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides with easily accessible Morita–Baylis–Hillman adducts as the dipolarophiles has been developed successfully and provides the highly substituted pyrrolidines bearing a unique quaternary and two tertiary stereogenic centers in excellent diastereoselectivity and up to 97% ee.

源语言英语
页(从-至)5494-5496
页数3
期刊Chemical Communications
47
19
DOI
出版状态已出版 - 26 4月 2011
已对外发布

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