Abstract
The first catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides with easily accessible Morita–Baylis–Hillman adducts as the dipolarophiles has been developed successfully and provides the highly substituted pyrrolidines bearing a unique quaternary and two tertiary stereogenic centers in excellent diastereoselectivity and up to 97% ee.
Original language | English |
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Pages (from-to) | 5494-5496 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 47 |
Issue number | 19 |
DOIs | |
Publication status | Published - 26 Apr 2011 |
Externally published | Yes |
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Dive into the research topics of 'Morita–Baylis–Hillman adducts as effective dipolarophiles in Copper(i)-catalyzed 1,3-dipolar cycloaddition with azomethine ylides: Asymmetric construction of pyrrolidine derivatives containing quaternary stereogenic center'. Together they form a unique fingerprint.Cite this
Teng, H. L., Huang, H., Tao, H. Y., & Wang, C. J. (2011). Morita–Baylis–Hillman adducts as effective dipolarophiles in Copper(i)-catalyzed 1,3-dipolar cycloaddition with azomethine ylides: Asymmetric construction of pyrrolidine derivatives containing quaternary stereogenic center. Chemical Communications, 47(19), 5494-5496. https://doi.org/10.1039/c1cc11138h