Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery

Xiangqian Jia; Weizhi Wang; Qiuju Han; Zihua Wang; Yunhong Jia; Zhiyuan Hu

doi:10.1021/acsmedchemlett.6b00028

Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery

Xiangqian Jia, Weizhi Wang^*, Qiuju Han, Zihua Wang, Yunhong Jia, Zhiyuan Hu

^*此作品的通讯作者

科研成果: 期刊稿件 › 文章 › 同行评审

19 引用（Scopus）

摘要

We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (H6, YLFFVFER) by a micromixer with high efficiency. Antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (HER2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models.

源语言	英语
页（从-至）	429-434
页数	6
期刊	ACS Medicinal Chemistry Letters
卷	7
期	4
DOI	https://doi.org/10.1021/acsmedchemlett.6b00028
出版状态	已出版 - 14 4月 2016
已对外发布	是

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Jia, X., Wang, W., Han, Q., Wang, Z., Jia, Y., & Hu, Z. (2016). Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery. ACS Medicinal Chemistry Letters, 7(4), 429-434. https://doi.org/10.1021/acsmedchemlett.6b00028

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abstract = "We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (H6, YLFFVFER) by a micromixer with high efficiency. Antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (HER2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models.",

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author = "Xiangqian Jia and Weizhi Wang and Qiuju Han and Zihua Wang and Yunhong Jia and Zhiyuan Hu",

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AU - Jia, Xiangqian

AU - Wang, Weizhi

AU - Han, Qiuju

AU - Wang, Zihua

AU - Jia, Yunhong

AU - Hu, Zhiyuan

PY - 2016/4/14

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AB - We present here a specific targeting nanocarrier system by functionalization of liposomes with one new type of breast cancer targeting peptide (H6, YLFFVFER) by a micromixer with high efficiency. Antitumor drugs could be successfully delivered into human epidermal growth factor receptor 2 (HER2) positive breast cancer cells with high efficiency in both in vivo and ex vivo models.

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KW - Nanocarrier

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Micromixer Based Preparation of Functionalized Liposomes and Targeting Drug Delivery

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