摘要
By integrating single cell trapping, identifying and in situ MDA (Multiple Displacement Amplification) gene amplifying in a single microchip, here we report a simple and cost-effective method to not only detect the existence of EGFR (Epidermal Growth Factor Receptor) mutation at single cell level, but also determine the abundances of diverse cells exhibiting different EGFR mutation types which were clinically proved to significantly affect the prognosis of EGFR-targeted therapy.
| 源语言 | 英语 |
|---|---|
| 主期刊名 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| 出版商 | Chemical and Biological Microsystems Society |
| 页 | 369-370 |
| 页数 | 2 |
| ISBN（电子版） | 9780979806490 |
| 出版状态 | 已出版 - 2016 |
| 已对外发布 | 是 |
| 活动 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, 爱尔兰 期限: 9 10月 2016 → 13 10月 2016 |
出版系列
| 姓名 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|
会议
| 会议 | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| 国家/地区 | 爱尔兰 |
| 市 | Dublin |
| 时期 | 9/10/16 → 13/10/16 |
指纹
探究 'Identifying EGFR-expressed cells and determining the abundances of different EGFR mutation types at single-cell level' 的科研主题。它们共同构成独一无二的指纹。引用此
Li, R., Zhou, M., Yue, C., Zhang, W., Wei, Z., & Hu, Z. (2016). Identifying EGFR-expressed cells and determining the abundances of different EGFR mutation types at single-cell level. 在 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (页码 369-370). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.