Characterization of single cell dynamic morphology by local deformation pattern modeling

Heng Li, Zhiwen Liu, Fengqian Pang, Yonggang Shi

科研成果: 书/报告/会议事项章节会议稿件同行评审

1 引用 (Scopus)

摘要

Computational analysis of cell dynamic morphology in time-lapse images has become a new topic of biomedical research. For single cell, it is a challenging task to consider the spatial inconsistency and the temporal accumulation of cell deformation. This paper introduces an innovative automate analysis method, in which temporal features of contour point deformation are captured and then local deformation pattern is modeled to characterize cell dynamic morphology and predict cell activation statue. We applied the method to classify lymphocyte videos of multiple groups. Experimental results demonstrate that the proposed method overcomes existing methods in accuracy and robustness.

源语言英语
主期刊名2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
主期刊副标题Smarter Technology for a Healthier World, EMBC 2017 - Proceedings
出版商Institute of Electrical and Electronics Engineers Inc.
329-332
页数4
ISBN(电子版)9781509028092
DOI
出版状态已出版 - 13 9月 2017
活动39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, 韩国
期限: 11 7月 201715 7月 2017

出版系列

姓名Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN(印刷版)1557-170X

会议

会议39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
国家/地区韩国
Jeju Island
时期11/07/1715/07/17

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