摘要
The water soluble 2,6-di-O-carboxymethyl-β-cyclodextrin(CM-β-CD) was used as a chiral selector to separate chloramphenicol metabolite. The effects of pH and CM-β-CD concentration on the enantiomeric separation were investigated. The addition of an organic modifier (methanol) to the buffer led to deterioration of the enantiomeric separation. The results indicated that CM-β-CD was superior to β-CD for the separation of chloramphenicol metabolite and the interaction mechanisms of CM-β-CD and β-CD were compared.
源语言 | 英语 |
---|---|
页(从-至) | 1390 |
页数 | 1 |
期刊 | Chinese Journal of Analytical Chemistry |
卷 | 24 |
期 | 12 |
出版状态 | 已出版 - 1996 |
指纹
探究 'Capillary electrophoretic enantiomeric separations with 2,6-di -O-carboxymethyl -β-cyclodextrin' 的科研主题。它们共同构成独一无二的指纹。引用此
Jin, H., Li, F., Gu, J., Fu, R., Liu, Y., & Dai, R. (1996). Capillary electrophoretic enantiomeric separations with 2,6-di -O-carboxymethyl -β-cyclodextrin. Chinese Journal of Analytical Chemistry, 24(12), 1390.