@article{40d513aabb354911a8457a7f4c11dc39,
title = "Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA",
abstract = "Urate oxidase (Uox) lost its function during evolution. Here the authors propose an atavistic strategy to treat hyperuricemia by using a proprietary lipid nanoparticle to load Uox mRNA, which reduced the serum uric acid levels effectively in two animal models.",
author = "Mengjie Zhang and Abid Hussain and Bo Hu and Haiyin Yang and Chunhui Li and Shuai Guo and Xiaofeng Han and Bei Li and Yunlu Dai and Yuhong Cao and Hang Chi and Yuhua Weng and Qin, {Cheng Feng} and Yuanyu Huang",
note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",
year = "2024",
month = dec,
doi = "10.1038/s41467-024-50752-9",
language = "English",
volume = "15",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",
number = "1",
}
