Asymptotic behavior for solutions to an oncolytic virotherapy model involving triply haptotactic terms

Ya nan Wei, Yifu Wang, Jing Li*

*此作品的通讯作者

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5 引用 (Scopus)

摘要

In this paper, based on Lp- Lq estimate for the Neumann heat semigroup, we investigate the asymptotic behavior for solutions to an oncolytic virotherapy model given by {ut=Δu-ξu∇·(u∇v)-ρuuz,x∈Ω,t>0,wt=Δw-ξw∇·(w∇v)-δww+ρwuz,x∈Ω,t>0,vt=-(αuu+αww)v-δvv,x∈Ω,t>0,zt=Δz-ξz∇·(z∇v)-δzz-ρzuz+βw,x∈Ω,t>0,where u, w, v and z denote the density of uninfected cancer cells, oncolytic viruses infected cancer cells, extracellular matrix and oncolytic virus particles, respectively. It is showed that when suitably regular initial data satisfy a certain small condition, infected cancer cells and virus particle populations will both become extinct asymptotically.

源语言英语
文章编号55
期刊Zeitschrift fur Angewandte Mathematik und Physik
73
2
DOI
出版状态已出版 - 4月 2022

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Wei, Y. N., Wang, Y., & Li, J. (2022). Asymptotic behavior for solutions to an oncolytic virotherapy model involving triply haptotactic terms. Zeitschrift fur Angewandte Mathematik und Physik, 73(2), 文章 55. https://doi.org/10.1007/s00033-022-01691-2