A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller

Dong Huang; Deyao Zhao; Jinhui Li; Lili Du; Zewen Wei; Zicai Liang; Zhihong Li

doi:10.1109/TRANSDUCERS.2017.7994389

A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller

Dong Huang, Deyao Zhao, Jinhui Li, Lili Du, Zewen Wei, Zicai Liang, Zhihong Li^*

^*此作品的通讯作者

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

9 引用（Scopus）

摘要

This paper reports a minimally invasive in vivo electroporation method utilizing parylene-based flexible electrode, after a treatment of microneedle device, Dermalroller^®.[1] Upon penetrating high-resistance stratum corneum, the sufficient hypodermic electric field can be established under low voltage condition. Benefiting from more uniform electric field under skin, good biocompatibility, and lower applied voltage, the transfection rate is higher and the electroporated skin is less likely to be harmed compared to the commercial device. Furthermore, the low cost and convenient operation offer vast potential for clinical applications.

源语言	英语
主期刊名	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
出版商	Institute of Electrical and Electronics Engineers Inc.
页	1684-1687
页数	4
ISBN（电子版）	9781538627310
DOI	https://doi.org/10.1109/TRANSDUCERS.2017.7994389
出版状态	已出版 - 26 7月 2017
已对外发布	是
活动	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 - Kaohsiung, 中国台湾期限: 18 6月 2017 → 22 6月 2017

出版系列

姓名	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

会议

会议	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
国家/地区	中国台湾
市	Kaohsiung
时期	18/06/17 → 22/06/17

访问文件

10.1109/TRANSDUCERS.2017.7994389

其它文件与链接

链接到 Scopus 的出版物

引用此

Huang, D., Zhao, D., Li, J., Du, L., Wei, Z., Liang, Z., & Li, Z. (2017). A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller. 在 TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems (页码 1684-1687). 文章 7994389 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2017.7994389

Huang, Dong ; Zhao, Deyao ; Li, Jinhui 等. / A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller. TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. 页码 1684-1687 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

@inproceedings{9b0526542a554c2d91ca9b113e84596c,

title = "A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller",

abstract = "This paper reports a minimally invasive in vivo electroporation method utilizing parylene-based flexible electrode, after a treatment of microneedle device, Dermalroller{\textregistered}.[1] Upon penetrating high-resistance stratum corneum, the sufficient hypodermic electric field can be established under low voltage condition. Benefiting from more uniform electric field under skin, good biocompatibility, and lower applied voltage, the transfection rate is higher and the electroporated skin is less likely to be harmed compared to the commercial device. Furthermore, the low cost and convenient operation offer vast potential for clinical applications.",

keywords = "Flexible electrode, In vivo electroporation, Microneedle roller, Minimally invasive",

author = "Dong Huang and Deyao Zhao and Jinhui Li and Lili Du and Zewen Wei and Zicai Liang and Zhihong Li",

note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 ; Conference date: 18-06-2017 Through 22-06-2017",

year = "2017",

month = jul,

day = "26",

doi = "10.1109/TRANSDUCERS.2017.7994389",

language = "English",

series = "TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "1684--1687",

booktitle = "TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems",

address = "United States",

}

Huang, D, Zhao, D, Li, J, Du, L, Wei, Z, Liang, Z & Li, Z 2017, A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller. 在 TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems., 7994389, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, Institute of Electrical and Electronics Engineers Inc., 页码 1684-1687, 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017, Kaohsiung, 中国台湾, 18/06/17. https://doi.org/10.1109/TRANSDUCERS.2017.7994389

A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller. / Huang, Dong; Zhao, Deyao; Li, Jinhui 等.
TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. 页码 1684-1687 7994389 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

TY - GEN

T1 - A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller

AU - Huang, Dong

AU - Zhao, Deyao

AU - Li, Jinhui

AU - Du, Lili

AU - Wei, Zewen

AU - Liang, Zicai

AU - Li, Zhihong

PY - 2017/7/26

Y1 - 2017/7/26

N2 - This paper reports a minimally invasive in vivo electroporation method utilizing parylene-based flexible electrode, after a treatment of microneedle device, Dermalroller®.[1] Upon penetrating high-resistance stratum corneum, the sufficient hypodermic electric field can be established under low voltage condition. Benefiting from more uniform electric field under skin, good biocompatibility, and lower applied voltage, the transfection rate is higher and the electroporated skin is less likely to be harmed compared to the commercial device. Furthermore, the low cost and convenient operation offer vast potential for clinical applications.

AB - This paper reports a minimally invasive in vivo electroporation method utilizing parylene-based flexible electrode, after a treatment of microneedle device, Dermalroller®.[1] Upon penetrating high-resistance stratum corneum, the sufficient hypodermic electric field can be established under low voltage condition. Benefiting from more uniform electric field under skin, good biocompatibility, and lower applied voltage, the transfection rate is higher and the electroporated skin is less likely to be harmed compared to the commercial device. Furthermore, the low cost and convenient operation offer vast potential for clinical applications.

KW - Flexible electrode

KW - In vivo electroporation

KW - Microneedle roller

KW - Minimally invasive

UR - http://www.scopus.com/inward/record.url?scp=85029350642&partnerID=8YFLogxK

U2 - 10.1109/TRANSDUCERS.2017.7994389

DO - 10.1109/TRANSDUCERS.2017.7994389

M3 - Conference contribution

AN - SCOPUS:85029350642

T3 - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

SP - 1684

EP - 1687

BT - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017

Y2 - 18 June 2017 through 22 June 2017

ER -

Huang D, Zhao D, Li J, Du L, Wei Z, Liang Z 等. A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller. 在 TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc. 2017. 页码 1684-1687. 7994389. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). doi: 10.1109/TRANSDUCERS.2017.7994389

A minimally invasive in vivo electroporation method utilizing flexile electrode and microneedle roller

摘要

出版系列

会议

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其它文件与链接

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引用此