@inproceedings{4af1daa3fc7a4594a4e4d87e5eecf804,
title = "A microfluidic cytometer with integrated on-chip optical systems for white blood cell analysis",
abstract = "White blood cells are a significant part of immune system, which can prevent human body from infection and invasion of foreign invaders. The count and recognition of white blood cells plays an important role in modern clinical practice. There is an urgent need to modify the conventional methods (such as cytometry), which are time-consuming and labor-intensive for white blood cell counting. This paper describes a microfluidic cytometer for white blood cells integrated a three-dimensional hydrodynamic focusing system and on-chip optical components, which can realize single-cell fluid flow and single-cell detection. Through the experiment, the device achieves the hydrodynamic focusing of cell flow and the detection of side scatter and fluorescence. For classifying and counting of white blood cells, we further perform an experiment using blood samples and get fairly good results.",
keywords = "Microfluidic chip, On-chip Microlens, Three-dimensional hydrodynamic focusing, White blood cells counts",
author = "Xinyue Su and Tao Peng and Qin Li and Zewen Wei and Xuantao Su",
note = "Publisher Copyright: {\textcopyright} 2021 SPIE.; Optics in Health Care and Biomedical Optics XI 2021 ; Conference date: 10-10-2021 Through 12-10-2021",
year = "2021",
doi = "10.1117/12.2602522",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Qingming Luo and Xingde Li and Ying Gu and Dan Zhu",
booktitle = "Optics in Health Care and Biomedical Optics XI",
address = "United States",
}
