Synthesis of nitroanilines catalyzed by horseradish peroxidase in the presence of NaNO2 and H2O2

Cong Liu, Rong ji Dai*, Jie Lin, Jian hua Sun, Shi Chen, Yu lin Deng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The synthesis of nitroanilines catalyzed by horseradish peroxidase(HRP) in the presence of sodium nitrite and hydrogen peroxide was investigated. o-Nitroaniline and p-nitroaniline were found in the nitrated products. 2-Aminotoluene and 4-aminotoluene could also be nitrated to give corresponding nitrated products. This protocol has great potentials to open new avenues useful for the synthesis of nitroaniline and its derivatives.

Original languageEnglish
Pages (from-to)1164-1166
Number of pages3
JournalChemical Research in Chinese Universities
Volume29
Issue number6
DOIs
Publication statusPublished - Dec 2013

Keywords

  • Enzyme
  • Horseradish peroxidase
  • Nitration
  • Nitroaniline
  • Phenylamine

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