Simultaneous Spatial-Temporal Decomposition of Connectome-Scale Brain Networks by Deep Sparse Recurrent Auto-Encoders

Qing Li, Qinglin Dong, Fangfei Ge, Ning Qiang, Yu Zhao, Han Wang, Heng Huang, Xia Wu*, Tianming Liu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

22 Citations (Scopus)

Abstract

Exploring the spatial patterns and temporal dynamics of human brain activities has long been a great topic, yet development of a unified spatial-temporal model for such purpose is still challenging. To better understand brain networks based on fMRI data and inspired by the success in applying deep learning for brain encoding/decoding, we propose a novel deep sparse recurrent auto-encoder (DSRAE) in an unsupervised spatial-temporal way to learn spatial and temporal patterns of brain networks jointly. The proposed DSRAE has been validated on the publicly available human connectome project (HCP) fMRI datasets with promising results. To our best knowledge, the proposed DSRAE is among the early unified models that can extract connectome-scale spatial-temporal networks from 4D fMRI data simultaneously.

Original languageEnglish
Title of host publicationInformation Processing in Medical Imaging - 26th International Conference, IPMI 2019, Proceedings
EditorsAlbert C.S. Chung, James C. Gee, Paul A. Yushkevich, Siqi Bao
PublisherSpringer Verlag
Pages579-591
Number of pages13
ISBN (Print)9783030203504
DOIs
Publication statusPublished - 2019
Externally publishedYes
Event26th International Conference on Information Processing in Medical Imaging, IPMI 2019 - Hong Kong, China
Duration: 2 Jun 20197 Jun 2019

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11492 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference26th International Conference on Information Processing in Medical Imaging, IPMI 2019
Country/TerritoryChina
CityHong Kong
Period2/06/197/06/19

Keywords

  • Auto-encoder
  • Recurrent neural network
  • Task-based fMRI

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