Photodynamic therapy for port wine stains assisted by a novel robotic system

Naiyan Huang; Jianguo Zhu; Ying Wang; Guibin Bian; Xingguang Duan; Weifeng Liu; Xiaoying Tang; Xingtao Wang; Shihu Cui; Chunyu Zhang; Ying Gu

doi:10.1117/12.868888

Photodynamic therapy for port wine stains assisted by a novel robotic system

Naiyan Huang, Jianguo Zhu, Ying Wang, Guibin Bian, Xingguang Duan, Weifeng Liu, Xiaoying Tang, Xingtao Wang, Shihu Cui, Chunyu Zhang, Ying Gu^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Citations (Scopus)

Abstract

Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm², 120-300J/cm²) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.

Original language	English
Title of host publication	Optics in Health Care and Biomedical Optics IV
DOIs	https://doi.org/10.1117/12.868888
Publication status	Published - 2010
Event	Optics in Health Care and Biomedical Optics IV - Beijing, China Duration: 18 Oct 2010 → 20 Oct 2010

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7845
ISSN (Print)	1605-7422

Conference

Conference	Optics in Health Care and Biomedical Optics IV
Country/Territory	China
City	Beijing
Period	18/10/10 → 20/10/10

Keywords

Photodynamic therapy
port wine stains
robotic system

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10.1117/12.868888

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Huang, N., Zhu, J., Wang, Y., Bian, G., Duan, X., Liu, W., Tang, X., Wang, X., Cui, S., Zhang, C., & Gu, Y. (2010). Photodynamic therapy for port wine stains assisted by a novel robotic system. In Optics in Health Care and Biomedical Optics IV Article 78451G (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7845). https://doi.org/10.1117/12.868888

@inproceedings{97e9d8fd7dad45c8978bd8d384969c01,

title = "Photodynamic therapy for port wine stains assisted by a novel robotic system",

abstract = "Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm2, 120-300J/cm2) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.",

keywords = "Photodynamic therapy, port wine stains, robotic system",

author = "Naiyan Huang and Jianguo Zhu and Ying Wang and Guibin Bian and Xingguang Duan and Weifeng Liu and Xiaoying Tang and Xingtao Wang and Shihu Cui and Chunyu Zhang and Ying Gu",

year = "2010",

doi = "10.1117/12.868888",

language = "English",

isbn = "9780819483751",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Optics in Health Care and Biomedical Optics IV",

note = "Optics in Health Care and Biomedical Optics IV ; Conference date: 18-10-2010 Through 20-10-2010",

}

Huang, N, Zhu, J, Wang, Y, Bian, G, Duan, X , Liu, W , Tang, X, Wang, X, Cui, S, Zhang, C & Gu, Y 2010, Photodynamic therapy for port wine stains assisted by a novel robotic system. in Optics in Health Care and Biomedical Optics IV., 78451G, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7845, Optics in Health Care and Biomedical Optics IV, Beijing, China, 18/10/10. https://doi.org/10.1117/12.868888

Photodynamic therapy for port wine stains assisted by a novel robotic system. / Huang, Naiyan; Zhu, Jianguo; Wang, Ying et al.
Optics in Health Care and Biomedical Optics IV. 2010. 78451G (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7845).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Photodynamic therapy for port wine stains assisted by a novel robotic system

AU - Huang, Naiyan

AU - Zhu, Jianguo

AU - Wang, Ying

AU - Bian, Guibin

AU - Duan, Xingguang

AU - Liu, Weifeng

AU - Tang, Xiaoying

AU - Wang, Xingtao

AU - Cui, Shihu

AU - Zhang, Chunyu

AU - Gu, Ying

PY - 2010

Y1 - 2010

N2 - Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm2, 120-300J/cm2) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.

AB - Port wine stains (PWS) is a vascular malformation consisting of dilated capillaries in the superficial dermis. Photodynamic therapy (PDT) is an effective approach in the treatment of PWS. However, the procedure of treatment is a low efficient and hard work, as the doctor need to hold laser fiber to irradiate for 20 min to 50 min per lesion. So an assisted novel robotic system was developed to instead part of doctor's work. The robotic system consisted of 7 degrees of freedom, in which there were 5 passive joints and 2 active joints. Binocular surveillance system was used as guidance for the robot. Clinical trial compared 20 patients (38 lesions) treated by the robotic system with another 20 patients (38 lesions) treated by a doctor. The patients in both groups were injected intravenously with photosensitizer (PSD-007, 4-5mg/kg) and irradiated with 532 nm laser (100mW/cm2, 120-300J/cm2) immediately. Both groups had same good therapeutic results. The robotic system is helpful in the PWS-PDT and hopefully would become a part of PWS therapy machine in the future.

KW - Photodynamic therapy

KW - port wine stains

KW - robotic system

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DO - 10.1117/12.868888

M3 - Conference contribution

AN - SCOPUS:78650473305

SN - 9780819483751

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Optics in Health Care and Biomedical Optics IV

T2 - Optics in Health Care and Biomedical Optics IV

Y2 - 18 October 2010 through 20 October 2010

ER -

Photodynamic therapy for port wine stains assisted by a novel robotic system

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