NaHBEt3-catalyzed HBpin hydroboration and deoxygenation of primary, secondary, and tertiary amides

Ben Yan; Xiaoli Ma; Ziyuan Pang; Zhi Yang

doi:10.1039/d2nj05849a

NaHBEt₃-catalyzed HBpin hydroboration and deoxygenation of primary, secondary, and tertiary amides

Ben Yan, Xiaoli Ma^*, Ziyuan Pang, Zhi Yang^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The reduction of amides to amines has always been a challenging yet attractive process. Herein, we show that in the presence of NaHBEt₃ acting as a catalyst, primary, secondary and tertiary amides can be reduced by HBpin, with a wide range of substrates and functional group tolerance. A plausible experimental mechanism is proposed based on control experimental reactions.

Original language	English
Pages (from-to)	3202-3206
Number of pages	5
Journal	New Journal of Chemistry
Volume	47
Issue number	7
DOIs	https://doi.org/10.1039/d2nj05849a
Publication status	Published - 13 Jan 2023

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title = "NaHBEt3-catalyzed HBpin hydroboration and deoxygenation of primary, secondary, and tertiary amides",

abstract = "The reduction of amides to amines has always been a challenging yet attractive process. Herein, we show that in the presence of NaHBEt3 acting as a catalyst, primary, secondary and tertiary amides can be reduced by HBpin, with a wide range of substrates and functional group tolerance. A plausible experimental mechanism is proposed based on control experimental reactions.",

author = "Ben Yan and Xiaoli Ma and Ziyuan Pang and Zhi Yang",

note = "Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry.",

year = "2023",

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T1 - NaHBEt3-catalyzed HBpin hydroboration and deoxygenation of primary, secondary, and tertiary amides

AU - Yan, Ben

AU - Ma, Xiaoli

AU - Pang, Ziyuan

AU - Yang, Zhi

PY - 2023/1/13

Y1 - 2023/1/13

N2 - The reduction of amides to amines has always been a challenging yet attractive process. Herein, we show that in the presence of NaHBEt3 acting as a catalyst, primary, secondary and tertiary amides can be reduced by HBpin, with a wide range of substrates and functional group tolerance. A plausible experimental mechanism is proposed based on control experimental reactions.

AB - The reduction of amides to amines has always been a challenging yet attractive process. Herein, we show that in the presence of NaHBEt3 acting as a catalyst, primary, secondary and tertiary amides can be reduced by HBpin, with a wide range of substrates and functional group tolerance. A plausible experimental mechanism is proposed based on control experimental reactions.

UR - http://www.scopus.com/inward/record.url?scp=85147413768&partnerID=8YFLogxK

U2 - 10.1039/d2nj05849a

DO - 10.1039/d2nj05849a

M3 - Article

AN - SCOPUS:85147413768

SN - 1144-0546

VL - 47

SP - 3202

EP - 3206

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 7

ER -

NaHBEt₃-catalyzed HBpin hydroboration and deoxygenation of primary, secondary, and tertiary amides

Abstract

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