Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives

Congcong Gao; Yong Tian; Rubo Zhang; Jing Jing; Xiaoling Zhang

doi:10.1039/C8NJ05951A

Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives

Congcong Gao, Yong Tian, Rubo Zhang^*, Jing Jing, Xiaoling Zhang

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We herein report a ratiometric fluorescent probe, MN, capable of determining SO₃²⁻/HSO₃⁻ in mitochondria. The probe specifically responds to SO₃²⁻/HSO₃⁻ and is not interfered with by other biological mercaptans or anions. The LOD of the probe is 85 nM, making it a feasible sensor to image SO₃²⁻/HSO₃⁻. With good membrane permeability and low cytotoxicity, MN was successfully used in the ratiometric detection of SO₃²⁻/HSO₃⁻ in mitochondria.

Original language	English
Pages (from-to)	5255-5259
Number of pages	5
Journal	New Journal of Chemistry
Volume	43
Issue number	13
DOIs	https://doi.org/10.1039/C8NJ05951A
Publication status	Published - 2019

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Gao, C., Tian, Y., Zhang, R., Jing, J., & Zhang, X. (2019). Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives. New Journal of Chemistry, 43(13), 5255-5259. https://doi.org/10.1039/C8NJ05951A

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title = "Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives",

abstract = "We herein report a ratiometric fluorescent probe, MN, capable of determining SO32−/HSO3− in mitochondria. The probe specifically responds to SO32−/HSO3− and is not interfered with by other biological mercaptans or anions. The LOD of the probe is 85 nM, making it a feasible sensor to image SO32−/HSO3−. With good membrane permeability and low cytotoxicity, MN was successfully used in the ratiometric detection of SO32−/HSO3− in mitochondria.",

author = "Congcong Gao and Yong Tian and Rubo Zhang and Jing Jing and Xiaoling Zhang",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.",

year = "2019",

doi = "10.1039/C8NJ05951A",

language = "English",

volume = "43",

pages = "5255--5259",

journal = "New Journal of Chemistry",

issn = "1144-0546",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives

AU - Gao, Congcong

AU - Tian, Yong

AU - Zhang, Rubo

AU - Jing, Jing

AU - Zhang, Xiaoling

PY - 2019

Y1 - 2019

N2 - We herein report a ratiometric fluorescent probe, MN, capable of determining SO32−/HSO3− in mitochondria. The probe specifically responds to SO32−/HSO3− and is not interfered with by other biological mercaptans or anions. The LOD of the probe is 85 nM, making it a feasible sensor to image SO32−/HSO3−. With good membrane permeability and low cytotoxicity, MN was successfully used in the ratiometric detection of SO32−/HSO3− in mitochondria.

AB - We herein report a ratiometric fluorescent probe, MN, capable of determining SO32−/HSO3− in mitochondria. The probe specifically responds to SO32−/HSO3− and is not interfered with by other biological mercaptans or anions. The LOD of the probe is 85 nM, making it a feasible sensor to image SO32−/HSO3−. With good membrane permeability and low cytotoxicity, MN was successfully used in the ratiometric detection of SO32−/HSO3− in mitochondria.

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U2 - 10.1039/C8NJ05951A

DO - 10.1039/C8NJ05951A

M3 - Article

AN - SCOPUS:85063371075

SN - 1144-0546

VL - 43

SP - 5255

EP - 5259

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 13

ER -

Mitochondrial directed ratiometric fluorescent probe for quantitive detection of sulfur dioxide derivatives

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