Functionalized photonic crystal for the sensing of Sarin agents

Chunxiao Yan; Fenglian Qi; Shuguang Li; Jiayu Xu; Chao Liu; Zihui Meng; Lili Qiu; Min Xue; Wei Lu; Zequn Yan

doi:10.1016/j.talanta.2016.06.045

Functionalized photonic crystal for the sensing of Sarin agents

Chunxiao Yan, Fenglian Qi, Shuguang Li, Jiayu Xu, Chao Liu, Zihui Meng^*, Lili Qiu, Min Xue, Wei Lu, Zequn Yan

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The indiscriminate use of nerve agents by terrorist groups has attracted attention of the scientific communities toward the development of novel sensor technique for these deadly chemicals. A photonic crystal (PhC) hydrogel immobilized with butyrylcholinesterase (BuChE) was firstly prepared for the sensing of Sarin agents. Periodic polystyrene colloidal (240 nm) array was embedded inside an acrylamide hydrogel, and then BuChE was immobilized inside the hydrogel matrix via condensation with 3-(diethoxyphosphoryloxy)−1,2,3-benzotriazin-4(3 h)-one (DEPBT). It indicated that a total of 3.7 units of BuChE were immobilized onto the PhC hydrogel. The functionalized hydrogel recognized the Sarin agent and then shrunk, thus the diffraction of PhC hydrogel blue shifted significantly, and a limit of detection (LOD) of 10⁻¹⁵ mol L⁻¹ was achieved.

Original language	English
Pages (from-to)	412-417
Number of pages	6
Journal	Talanta
Volume	159
DOIs	https://doi.org/10.1016/j.talanta.2016.06.045
Publication status	Published - 1 Oct 2016

Keywords

Biosensor
Butyrylcholinesterase
Nerve agents
Photonic crystal
Sarin agent

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.talanta.2016.06.045

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title = "Functionalized photonic crystal for the sensing of Sarin agents",

abstract = "The indiscriminate use of nerve agents by terrorist groups has attracted attention of the scientific communities toward the development of novel sensor technique for these deadly chemicals. A photonic crystal (PhC) hydrogel immobilized with butyrylcholinesterase (BuChE) was firstly prepared for the sensing of Sarin agents. Periodic polystyrene colloidal (240 nm) array was embedded inside an acrylamide hydrogel, and then BuChE was immobilized inside the hydrogel matrix via condensation with 3-(diethoxyphosphoryloxy)−1,2,3-benzotriazin-4(3 h)-one (DEPBT). It indicated that a total of 3.7 units of BuChE were immobilized onto the PhC hydrogel. The functionalized hydrogel recognized the Sarin agent and then shrunk, thus the diffraction of PhC hydrogel blue shifted significantly, and a limit of detection (LOD) of 10−15 mol L−1 was achieved.",

keywords = "Biosensor, Butyrylcholinesterase, Nerve agents, Photonic crystal, Sarin agent",

author = "Chunxiao Yan and Fenglian Qi and Shuguang Li and Jiayu Xu and Chao Liu and Zihui Meng and Lili Qiu and Min Xue and Wei Lu and Zequn Yan",

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year = "2016",

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doi = "10.1016/j.talanta.2016.06.045",

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T1 - Functionalized photonic crystal for the sensing of Sarin agents

AU - Yan, Chunxiao

AU - Qi, Fenglian

AU - Li, Shuguang

AU - Xu, Jiayu

AU - Liu, Chao

AU - Meng, Zihui

AU - Qiu, Lili

AU - Xue, Min

AU - Lu, Wei

AU - Yan, Zequn

PY - 2016/10/1

Y1 - 2016/10/1

N2 - The indiscriminate use of nerve agents by terrorist groups has attracted attention of the scientific communities toward the development of novel sensor technique for these deadly chemicals. A photonic crystal (PhC) hydrogel immobilized with butyrylcholinesterase (BuChE) was firstly prepared for the sensing of Sarin agents. Periodic polystyrene colloidal (240 nm) array was embedded inside an acrylamide hydrogel, and then BuChE was immobilized inside the hydrogel matrix via condensation with 3-(diethoxyphosphoryloxy)−1,2,3-benzotriazin-4(3 h)-one (DEPBT). It indicated that a total of 3.7 units of BuChE were immobilized onto the PhC hydrogel. The functionalized hydrogel recognized the Sarin agent and then shrunk, thus the diffraction of PhC hydrogel blue shifted significantly, and a limit of detection (LOD) of 10−15 mol L−1 was achieved.

AB - The indiscriminate use of nerve agents by terrorist groups has attracted attention of the scientific communities toward the development of novel sensor technique for these deadly chemicals. A photonic crystal (PhC) hydrogel immobilized with butyrylcholinesterase (BuChE) was firstly prepared for the sensing of Sarin agents. Periodic polystyrene colloidal (240 nm) array was embedded inside an acrylamide hydrogel, and then BuChE was immobilized inside the hydrogel matrix via condensation with 3-(diethoxyphosphoryloxy)−1,2,3-benzotriazin-4(3 h)-one (DEPBT). It indicated that a total of 3.7 units of BuChE were immobilized onto the PhC hydrogel. The functionalized hydrogel recognized the Sarin agent and then shrunk, thus the diffraction of PhC hydrogel blue shifted significantly, and a limit of detection (LOD) of 10−15 mol L−1 was achieved.

KW - Biosensor

KW - Butyrylcholinesterase

KW - Nerve agents

KW - Photonic crystal

KW - Sarin agent

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U2 - 10.1016/j.talanta.2016.06.045

DO - 10.1016/j.talanta.2016.06.045

M3 - Article

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AN - SCOPUS:84978959040

SN - 0039-9140

VL - 159

SP - 412

EP - 417

JO - Talanta

JF - Talanta

ER -

Functionalized photonic crystal for the sensing of Sarin agents

Abstract

Keywords

UN SDGs

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