Facile synthesis of (2-Amino-3-(benzothiazol-2-yl)-4H-chromen-4-yl)phosphonate derivatives under mild conditions

Haohao Yan, Boliang Zhao, Yu Gao, Daming Du*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A series of (2-amino-3-(benzothiazol-2-yl)-4H-chromen-4-yl)phosphonate derivatives were synthesized in good to excellent yields by Michael addition/cyclization of diphenyl phosphite to diverse substituted (E)-2-(benzothiazol-2-yl)-3-(2-hydroxyphenyl)acrylonitriles under catalyst-free condition in water.

Original languageEnglish
Pages (from-to)1643-1652
Number of pages10
JournalChinese Journal of Organic Chemistry
Volume36
Issue number7
DOIs
Publication statusPublished - 1 Jul 2016

Keywords

  • Chromene
  • Cyclization
  • Heterocycle
  • Michael addition
  • Phosphonate

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Yan, H., Zhao, B., Gao, Y., & Du, D. (2016). Facile synthesis of (2-Amino-3-(benzothiazol-2-yl)-4H-chromen-4-yl)phosphonate derivatives under mild conditions. Chinese Journal of Organic Chemistry, 36(7), 1643-1652. https://doi.org/10.6023/cjoc201512021