Default mode network in healthy elders: A pilot research on independent component analysis combined with correlation analysis

Zhi Gang Qi; Xiao Yi Wang; Xing Wang; Xia Wu; Kun Cheng Li

Default mode network in healthy elders: A pilot research on independent component analysis combined with correlation analysis

Zhi Gang Qi, Xiao Yi Wang, Xing Wang, Xia Wu, Kun Cheng Li^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To investigate the consistency between independent component analysis (ICA) and correlation analysis of default mode network (DMN) in healthy elderly. Methods: Resting-state fMR examination was performed with 3.0T MR scanner and 8-channel head coil. After pre-process of fMRI data with SPM, ICA was performed with GIFT and correlation analysis was performed with AFNI. Functional areas of DMN in healthy elderly were compared between the two methods. Results: Except for hippocampal formation, consistent results of DMN were observed between ICA and correlation analysis. Functional connectivity was found between posterior cingulated cortex (PCC) and most of the functional areas in DMN. Conclusion: ICA and correlation analysis has consistent results for DMN. Combination of these two methods may contribute to the further study of brain function on resting-state fMRI.

Original language	English
Pages (from-to)	1636-1639
Number of pages	4
Journal	Chinese Journal of Medical Imaging Technology
Volume	26
Issue number	9
Publication status	Published - Sept 2010
Externally published	Yes

Keywords

Aged
Functional connectivity
Independent component analysis
Magnetic resonance imaging

Cite this

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title = "Default mode network in healthy elders: A pilot research on independent component analysis combined with correlation analysis",

abstract = "Objective: To investigate the consistency between independent component analysis (ICA) and correlation analysis of default mode network (DMN) in healthy elderly. Methods: Resting-state fMR examination was performed with 3.0T MR scanner and 8-channel head coil. After pre-process of fMRI data with SPM, ICA was performed with GIFT and correlation analysis was performed with AFNI. Functional areas of DMN in healthy elderly were compared between the two methods. Results: Except for hippocampal formation, consistent results of DMN were observed between ICA and correlation analysis. Functional connectivity was found between posterior cingulated cortex (PCC) and most of the functional areas in DMN. Conclusion: ICA and correlation analysis has consistent results for DMN. Combination of these two methods may contribute to the further study of brain function on resting-state fMRI.",

keywords = "Aged, Functional connectivity, Independent component analysis, Magnetic resonance imaging",

author = "Qi, {Zhi Gang} and Wang, {Xiao Yi} and Xing Wang and Xia Wu and Li, {Kun Cheng}",

year = "2010",

month = sep,

language = "English",

volume = "26",

pages = "1636--1639",

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number = "9",

}

TY - JOUR

T1 - Default mode network in healthy elders

T2 - A pilot research on independent component analysis combined with correlation analysis

AU - Qi, Zhi Gang

AU - Wang, Xiao Yi

AU - Wang, Xing

AU - Wu, Xia

AU - Li, Kun Cheng

PY - 2010/9

Y1 - 2010/9

N2 - Objective: To investigate the consistency between independent component analysis (ICA) and correlation analysis of default mode network (DMN) in healthy elderly. Methods: Resting-state fMR examination was performed with 3.0T MR scanner and 8-channel head coil. After pre-process of fMRI data with SPM, ICA was performed with GIFT and correlation analysis was performed with AFNI. Functional areas of DMN in healthy elderly were compared between the two methods. Results: Except for hippocampal formation, consistent results of DMN were observed between ICA and correlation analysis. Functional connectivity was found between posterior cingulated cortex (PCC) and most of the functional areas in DMN. Conclusion: ICA and correlation analysis has consistent results for DMN. Combination of these two methods may contribute to the further study of brain function on resting-state fMRI.

AB - Objective: To investigate the consistency between independent component analysis (ICA) and correlation analysis of default mode network (DMN) in healthy elderly. Methods: Resting-state fMR examination was performed with 3.0T MR scanner and 8-channel head coil. After pre-process of fMRI data with SPM, ICA was performed with GIFT and correlation analysis was performed with AFNI. Functional areas of DMN in healthy elderly were compared between the two methods. Results: Except for hippocampal formation, consistent results of DMN were observed between ICA and correlation analysis. Functional connectivity was found between posterior cingulated cortex (PCC) and most of the functional areas in DMN. Conclusion: ICA and correlation analysis has consistent results for DMN. Combination of these two methods may contribute to the further study of brain function on resting-state fMRI.

KW - Aged

KW - Functional connectivity

KW - Independent component analysis

KW - Magnetic resonance imaging

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M3 - Article

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JO - Chinese Journal of Medical Imaging Technology

JF - Chinese Journal of Medical Imaging Technology

IS - 9

ER -

Default mode network in healthy elders: A pilot research on independent component analysis combined with correlation analysis

Abstract

Keywords

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