Aptamer and its selection via various SELEX strategies

Ge Yang; Wenjing Liu; Yuanyu Huang

doi:10.1016/B978-0-323-91903-6.00004-4

Aptamer and its selection via various SELEX strategies

Ge Yang, Wenjing Liu, Yuanyu Huang

Advanced Research Institute of Multidisciplinary Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Aptamers of small-molecule targets have broad application prospects and great potential for economic benefits in the fields of biological analysis, food and environmental detection, molecular imaging, and disease diagnosis and treatment; therefore, the aptamer sensing technology for small molecule analysis and detection is a research focus. To date, hundreds of aptamers targeting small molecules have been identified, and thousands of aptasensors have been developed based on them. This chapter introduces the concept of aptamer with both optimization and development of various SELEX strategies for the selection of aptamers of small-molecule targets, most of which are hazard factors or nutritional elements of food integrity.

Original language	English
Title of host publication	Aptamers for Food Applications
Subtitle of host publication	Safety, Authenticity, and Integrity
Publisher	Elsevier
Pages	29-64
Number of pages	36
ISBN (Electronic)	9780323919036
ISBN (Print)	9780323985147
DOIs	https://doi.org/10.1016/B978-0-323-91903-6.00004-4
Publication status	Published - 1 Jan 2023

Keywords

Aptamer
Computer-aided SELEX
Gold nanoparticles capture-SELEX
Nucleic acid sequence
Quartz crystal microbalance-SELEX
SELEX
Small-molecule targets

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10.1016/B978-0-323-91903-6.00004-4

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Aptamer and its selection via various SELEX strategies

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Keywords

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