A highly selective ratiometric fluorescent probe for 1,4-dithiothreitol (DTT) detection

Baocun Zhu; Xiaoling Zhang; Hongying Jia; Yamin Li; Haipeng Liu; Weihong Tan

doi:10.1039/b923754b

A highly selective ratiometric fluorescent probe for 1,4-dithiothreitol (DTT) detection

Baocun Zhu, Xiaoling Zhang^*, Hongying Jia, Yamin Li, Haipeng Liu, Weihong Tan

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

A highly selective ratiometric fluorescent probe, which contains an aminonaphthalimide fluorophore and a self-immolative spacer for 1,4-dithiothreitol (DTT) detection was designed and synthesized. The probe displays a 66 nm red-shift of fluorescence emission and the color changes from colorless to jade-green upon reaction with DTT. These properties are mechanistically ascribed to the strong reducing capability of DTT.

Original language	English
Pages (from-to)	1650-1654
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	8
Issue number	7
DOIs	https://doi.org/10.1039/b923754b
Publication status	Published - 2010

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10.1039/b923754b

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abstract = "A highly selective ratiometric fluorescent probe, which contains an aminonaphthalimide fluorophore and a self-immolative spacer for 1,4-dithiothreitol (DTT) detection was designed and synthesized. The probe displays a 66 nm red-shift of fluorescence emission and the color changes from colorless to jade-green upon reaction with DTT. These properties are mechanistically ascribed to the strong reducing capability of DTT.",

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AU - Zhu, Baocun

AU - Zhang, Xiaoling

AU - Jia, Hongying

AU - Li, Yamin

AU - Liu, Haipeng

AU - Tan, Weihong

PY - 2010

Y1 - 2010

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AB - A highly selective ratiometric fluorescent probe, which contains an aminonaphthalimide fluorophore and a self-immolative spacer for 1,4-dithiothreitol (DTT) detection was designed and synthesized. The probe displays a 66 nm red-shift of fluorescence emission and the color changes from colorless to jade-green upon reaction with DTT. These properties are mechanistically ascribed to the strong reducing capability of DTT.

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A highly selective ratiometric fluorescent probe for 1,4-dithiothreitol (DTT) detection

Abstract

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