Professor Xu Zhibin is mainly engaged in the design and synthesis of energetic materials and fine chemicals (drugs). Presided over one explosive youth fund, three national defense basic scientific research projects, and participated in four national defense basic scientific research projects as the main participant. He has published more than 20 SCI papers, 7 EI papers, and 3 authorized invention patents. Guided the students to win the first prize of the 13th Beijing College Students Chemistry Experiment Competition in 2021.
(1) Focusing on major national defense needs, design and synthesis of high energy density materials based on quantitative calculation and organic synthesis
(2) Under the background of "carbon neutrality and carbon peaking", the research and development of green preparation technology of fine chemicals (drugs) is carried out with microreactor technology as a strengthening means, combined with automation and intelligent means.
From September 2000 to July 2003, he majored in Pharmaceutical Chemistry at the Institute of Pharmaceutical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical University, and obtained his Doctor of Science degree.
From September 1997 to July 2000, he majored in Pharmaceutical Chemistry at the Institute of Pharmaceutical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical University, and obtained his Master of Science degree.
From September 1992 to July 1996, majoring in the identification of Traditional Chinese Medicine, China Pharmaceutical University, obtained the Bachelor of Science degree
From December 2005 to now, School of Chemical Engineering and Environment, Beijing Institute of Technology
December 2013 - December 2014, Visiting Scholar, Department of Chemistry, University of Wisconsin-Madison, USA
December 2004 - December 2005, Postdoctoral Fellow, School of Chemistry and Molecular Engineering, Peking University
1. Yiyun Wang, Xiaofang Lv, Zihui Meng, Zhibin Xu*, Zhonghui Zheng, Jiarong Li, Min Xue. Fast and efficient synthesis of key intermediates of baloxavir marboxil catalyzed by strong solid acid under microwave conditions. Crystals, 2022, 12(7): 891. https://doi.org/10.3390/cryst12070891..
2. Yiyun Wang, Hongyi Wang, Haojie Xu, Zhonghui Zheng, Zihui Meng, Zhibin Xu, Jiarong Li, Min Xue. Design and synthesis of novel five-membered heterocyclic derivatives of istradefylline with comparable pharmacological activity. Chemical Biology & Drug Design, 2022, 100(4): 534-552.
3. Yiyun Wang, Hongyi Wang, Haojie Xu, Zhonghui Zheng, Zihui Meng, Zhibin Xu, Jiarong Li, Min Xue. Design, synthesis, and biological activity studies of istradefylline derivatives based on adenine as A2A receptor antagonists, ACS Omega, 2021, 6(6): 4386-4394.
4. Qiaoli Yan,Wenjin Liu, Hongliang Wen, Zhibin Xu*, Zihui Meng. A New Fluorescent Sensor for Fe3+ Based on Glycoluril Molecular Clip. ChemistrySelect, 2022,5(6): 1878-1883.
5. 杨童童,侯晓文,孟子晖,徐志斌*. 多硝基3,3,7,7-四(三氟甲基)-2,4,6,8-四氮杂双环[3.3.0]辛烷的合成与性能. 含能材料, 2020, 28(7): 657-663.
6. Tongtong Yang, Zihui Meng, Zhibin Xu*. A novel synthesis, characterization and performances of 1,3,5-trinitro-2,2-bis(trifluoromethyl)-1,3,5-triazinane. ChemistrySelect, 2019, 4(20): 6338-6341.
7. Yang Liu; Tongtong Yang;Zhibinu* (徐志斌); Zihui Meng*. Synthesis and characterization of diaminoguanidine and hydroxylamine salts of 1, 1, 2, 2-tetranitroaminoethane(TNAE). ChemistrySelect, 2019, 4(12): 3582-3584.
8. Wenjin Liu; Zhibin Xu* (徐志斌); Rui Wang; Chenfan Zhang; Qiaoli Yan; Zihui Meng*. Synthesis, hydrolysis, reduction and nitrolysis of glycoluril-derived precursors: another attempt toward the synthesis of nitramine explosives. ChemistrySelect, 2019, 4(12): 3474-3478.
9. Chao Zhu; Panqi Song Lili Qiu*; Yang Liu; Zhibin Xu* (徐志斌). Synthesis and characterization of the guanidine salt based on 1, 1, 2, 2-tetranitraminoethane (TNAE). Propellants explosives pyrotechnics, 2018, 43(12): 1296-1301.
10. Chao Zhu; Zihui Meng; Wenjin Liu; Hongwei Ma; Jiarong Li; Tongtong Yang; Yang Liu; Ni Liu; Zhibin Xu*. Investigation on the hydrolytic mechanism of cucurbit[6]uril in alkaline solution. Royal Society Open Science,2018, 5(5): 180038.
11. Chao Zhu; Zihui Meng*; Yue Liu; Zhibin Xu (徐志斌); Hongyan Song; Peng Wang. Mechanism Improvement and Process optimization of the one-pot synthesis of 3.7-dinitro-1, 3, 5, 7-tetraazabicyclo[3, 3, 1]nonane from urea. Propellant Explosives Pyrotechnique. 2018, 43(10): 1056-1059.
12. 徐志斌,孟子晖,米彦青, 董英杰,张纯, 薛敏, 崔至皓. 一类新型截短侧耳素衍生物及其制备方法和抗肿瘤用途途. 中国专利ZL201310221737.
13. 徐志斌,孟子晖,皇春阳,张阳. 3-(3‘-羟基丁基)异苯并呋喃-1(3H0-酮衍生物及其组合物、制备方法和用途. 中国专利ZL202110365007.
14. 徐志斌,孟子晖,吕晓芳,王佳如, 王宜运. 一种巴洛沙韦关键中间体的制备方法. 中国专利ZL202110983010.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):