Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid

Yi Liu; Yulin Deng; Rong Zheng; Peilong Zhang; Hui Zhai; Changjin Zhu

doi:10.1248/cpb.54.832

Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid

Yi Liu, Yulin Deng, Rong Zheng, Peilong Zhang, Hui Zhai, Changjin Zhu^*

^*此作品的通讯作者

医学技术学院

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

In order to improve the cell penetration of polyamide and its movement toward nucleic DNA we synthesized a conjugate of polyamide and phospholipid, which showed a significantly reducecd cytotoxicity and effective apoptosis when comparing with the native polyamide.

源语言	英语
页（从-至）	832-835
页数	4
期刊	Chemical and Pharmaceutical Bulletin
卷	54
期	6
DOI	https://doi.org/10.1248/cpb.54.832
出版状态	已出版 - 6月 2006

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10.1248/cpb.54.832

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Liu, Y., Deng, Y., Zheng, R., Zhang, P., Zhai, H., & Zhu, C. (2006). Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid. Chemical and Pharmaceutical Bulletin, 54(6), 832-835. https://doi.org/10.1248/cpb.54.832

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title = "Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid",

abstract = "In order to improve the cell penetration of polyamide and its movement toward nucleic DNA we synthesized a conjugate of polyamide and phospholipid, which showed a significantly reducecd cytotoxicity and effective apoptosis when comparing with the native polyamide.",

keywords = "Apoptosis, Cytotoxicity, Phospholipid conjugate, Polyamide",

author = "Yi Liu and Yulin Deng and Rong Zheng and Peilong Zhang and Hui Zhai and Changjin Zhu",

year = "2006",

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doi = "10.1248/cpb.54.832",

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T1 - Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid

AU - Liu, Yi

AU - Deng, Yulin

AU - Zheng, Rong

AU - Zhang, Peilong

AU - Zhai, Hui

AU - Zhu, Changjin

PY - 2006/6

Y1 - 2006/6

N2 - In order to improve the cell penetration of polyamide and its movement toward nucleic DNA we synthesized a conjugate of polyamide and phospholipid, which showed a significantly reducecd cytotoxicity and effective apoptosis when comparing with the native polyamide.

AB - In order to improve the cell penetration of polyamide and its movement toward nucleic DNA we synthesized a conjugate of polyamide and phospholipid, which showed a significantly reducecd cytotoxicity and effective apoptosis when comparing with the native polyamide.

KW - Apoptosis

KW - Cytotoxicity

KW - Phospholipid conjugate

KW - Polyamide

UR - http://www.scopus.com/inward/record.url?scp=33744775939&partnerID=8YFLogxK

U2 - 10.1248/cpb.54.832

DO - 10.1248/cpb.54.832

M3 - Article

C2 - 16755053

AN - SCOPUS:33744775939

SN - 0009-2363

VL - 54

SP - 832

EP - 835

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

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Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid

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