Silver-mediated radical trifluoromethylarylation of activated alkenes for the synthesis of oxindoles bearing a CF3 group

Yao Feng Wang, Jiashen Qiu, Dejie Kong, Fu Xue Chen*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

25 引用 (Scopus)

摘要

A radical trifluoromethylarylation of N-arylacrylamides with in situ generated [AgCF3] species from Me3SiCF3 and AgF in DMF is established through a tandem radical addition and C-H activation pathway. It provided a concise method to prepare 21 examples of CF 3-containing oxindoles within four hours.

源语言英语
文章编号st-2014-w0243-l
页(从-至)1731-1734
页数4
期刊Synlett
25
12
DOI
出版状态已出版 - 7月 2014

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