Preparation and evaluation of serine derivatived β-cyclodextrin column for high performance liquid chromatography

Li Na Geng*, Yan Li, Yu Pang, Shuang Yu, Li Quan Sun, Ai Qin Luo

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

摘要

Chromatography column packing of the newly prepared carbobenzyloxy-L-Ser derived β-CD bonded phase (SCDS), along with the underived β-CD bonded phase (CDS) were investigated. Satisfactory column efficiency, peak shape and reproducibility were obtained by optimizing high pressure column packing technology, such as packing pressure and slurry dispersing medium. The separation performance of SCDS for several position isomers and chiral compounds were also investigated and compared with CDS. The newly prepared column exhibited specific properties in realizing isomers separation.

源语言英语
页(从-至)1022-1026
页数5
期刊Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
27
11
出版状态已出版 - 11月 2007

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