Effect of C7 Modifications on Benzothiadiazine-1,1-dioxide Derivatives on Their Inhibitory Activity and Selectivity toward Aldose Reductase

Biochemistry, Genetics and Molecular Biology

• Aldo-Keto Reductase 50%
• Aldose Reductase 100%
• IC50 50%
• Molecular Model 50%
• Molecular Modeling 50%
• Oxidoreductase 50%
• Reductase 50%
• Structure Activity Relation 100%

Pharmacology, Toxicology and Pharmaceutical Science

• 1,2,4 Benzothiadiazine 1,1 Dioxide Derivative 33%
• Retinopathy 33%