An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

Dongyang Chen; Jianbing Shi; Yanmei Wu; Bin Tong; Junge Zhi; Yuping Dong

doi:10.1007/s11426-013-4915-8

An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

Dongyang Chen, Jianbing Shi^*, Yanmei Wu, Bin Tong, Junge Zhi, Yuping Dong

^*此作品的通讯作者

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

15 引用（Scopus）

摘要

Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

源语言	英语
页（从-至）	1239-1246
页数	8
期刊	Science China Chemistry
卷	56
期	9
DOI	https://doi.org/10.1007/s11426-013-4915-8
出版状态	已出版 - 9月 2013

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Chen, D., Shi, J., Wu, Y., Tong, B., Zhi, J., & Dong, Y. (2013). An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range. Science China Chemistry, 56(9), 1239-1246. https://doi.org/10.1007/s11426-013-4915-8

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title = "An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range",

abstract = "Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.",

keywords = "aggregation-induced emission enhancement (AIEE), biosensor, heparin quantification, pyridinium, tetraphenylethene (TPE)",

author = "Dongyang Chen and Jianbing Shi and Yanmei Wu and Bin Tong and Junge Zhi and Yuping Dong",

year = "2013",

month = sep,

doi = "10.1007/s11426-013-4915-8",

language = "English",

volume = "56",

pages = "1239--1246",

journal = "Science China Chemistry",

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TY - JOUR

T1 - An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

AU - Chen, Dongyang

AU - Shi, Jianbing

AU - Wu, Yanmei

AU - Tong, Bin

AU - Zhi, Junge

AU - Dong, Yuping

PY - 2013/9

Y1 - 2013/9

N2 - Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

AB - Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

KW - aggregation-induced emission enhancement (AIEE)

KW - biosensor

KW - heparin quantification

KW - pyridinium

KW - tetraphenylethene (TPE)

UR - http://www.scopus.com/inward/record.url?scp=84883458737&partnerID=8YFLogxK

U2 - 10.1007/s11426-013-4915-8

DO - 10.1007/s11426-013-4915-8

M3 - Article

AN - SCOPUS:84883458737

SN - 1674-7291

VL - 56

SP - 1239

EP - 1246

JO - Science China Chemistry

JF - Science China Chemistry

IS - 9

ER -

An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

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