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A series of pyrido[2,3-b[pyrazin-3(4 H)-one derivatives as aldose reductase inhibitors with antioxidant activity
Zhongfei Han, Xin Hao,
Bing Ma
, Changjin Zhu
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此作品的通讯作者
化学与化工学院
Beijing Institute of Technology
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Biochemistry, Genetics and Molecular Biology
Acetic Acid
50%
Aldose Reductase
50%
Aldose Reductase Inhibitor
100%
Antioxidant Activity
100%
Docking (Molecular)
50%
Enzyme
50%
IC50
100%
Oxidative Stress
50%
Structure Activity Relation
50%
Trolox
50%
Pharmacology, Toxicology and Pharmaceutical Science
Aldehyde Reductase
33%
Aldose Reductase Inhibitor
100%
Antioxidant
100%
Antioxidant Capacity
100%
Diabetic Complication
33%
IC50
66%
Phenazone
100%
Potassium Acetate
33%
Structure Activity Relationship
33%
Trolox C
33%
Chemistry
% Inhibition
33%
Acetic Acid
33%
Aldose
33%
Aldose Reductase Inhibitor
100%
Antioxidant Agent
100%
Antioxidant Capacity
100%
Hydroxyl
66%
IC50
66%
Oxidative Stress
33%
Structure-Activity Relationship
33%
Trolox
33%